Glucagon Antibody (K79bB10): sc-57171
- Glucagon Antibody (K79bB10) is a mouse monoclonal IgG1, cited in 5 publications, provided at 200 µg/ml
- raised against polymerized Glucagon of porcine origin
- Anti-Glucagon Antibody (K79bB10) is recommended for detection of Glucagon of mouse, rat, human, porcine, feline and canine origin by WB, IP, IF and IHC(P); not recommended for detection of enteroglucagon
- Anti-Glucagon Antibody (K79bB10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Glucagon Antibody (K79bB10). This work is in progress.
Glucagon Antibody (K79bB10) is a mouse monoclonal IgG1 antibody that detects Glucagon in mouse, rat, human, porcine, feline, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-Glucagon antibody (K79bB10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Glucagon plays a crucial role as a pancreatic hormone that counteracts insulin, promoting the conversion of glycogen to glucose and thereby elevating blood sugar levels, which is vital for maintaining energy homeostasis in the body. Additionally, Glucagon is part of a larger family of hormones that includes Glucagon-like peptide-1 (GLP-1), Glucagon-like peptide-2 (GLP-2), vasoactive intestinal peptide (VIP), and pituitary adenylate cyclase-activating polypeptide (PACAP). These related peptides have diverse functions, such as GLP-1′s role in regulating appetite and glucose metabolism, GLP-2′s stimulation of intestinal growth, VIP′s vasodilatory effects that lower blood pressure, and PACAP′s involvement in hormone synthesis in the hypothalamus. The interactions among these proteins highlight the complex regulatory mechanisms governing metabolic processes and underscore Glucagon′s importance in both physiological and pathological states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Glucagon Antibody (K79bB10) References:
- Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide. | Rouillé, Y., et al. 1995. J Biol Chem. 270: 26488-96. PMID: 7592866
- Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells. | Moens, K., et al. 1996. Diabetes. 45: 257-61. PMID: 8549871
- Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene. | Scrocchi, LA., et al. 1996. Nat Med. 2: 1254-8. PMID: 8898756
- Vasoactive intestinal peptide (VIP) stimulates in vitro growth of VIP-1 receptor-bearing human pancreatic adenocarcinoma-derived cells. | Jiang, S., et al. 1997. Cancer Res. 57: 1475-80. PMID: 9108448
- Specific features of glycogen metabolism in the liver. | Bollen, M., et al. 1998. Biochem J. 336 (Pt 1): 19-31. PMID: 9806880
- Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP27 activate common and distinct intracellular signaling pathways to stimulate growth hormone secretion from porcine somatotropes. | Martínez-Fuentes, AJ., et al. 1998. Endocrinology. 139: 5116-24. PMID: 9832451
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glucagon Antibody (K79bB10) | sc-57171 | 200 µg/ml | $316.00 | |||
Glucagon Antibody (K79bB10) AC | sc-57171 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Glucagon Antibody (K79bB10) HRP | sc-57171 HRP | 200 µg/ml | $316.00 | |||
Glucagon Antibody (K79bB10) FITC | sc-57171 FITC | 200 µg/ml | $330.00 | |||
Glucagon Antibody (K79bB10) PE | sc-57171 PE | 200 µg/ml | $343.00 | |||
Glucagon Antibody (K79bB10) Alexa Fluor® 488 | sc-57171 AF488 | 200 µg/ml | $357.00 | |||
Glucagon Antibody (K79bB10) Alexa Fluor® 546 | sc-57171 AF546 | 200 µg/ml | $357.00 | |||
Glucagon Antibody (K79bB10) Alexa Fluor® 594 | sc-57171 AF594 | 200 µg/ml | $357.00 | |||
Glucagon Antibody (K79bB10) Alexa Fluor® 647 | sc-57171 AF647 | 200 µg/ml | $357.00 | |||
Glucagon Antibody (K79bB10) Alexa Fluor® 680 | sc-57171 AF680 | 200 µg/ml | $357.00 | |||
Glucagon Antibody (K79bB10) Alexa Fluor® 790 | sc-57171 AF790 | 200 µg/ml | $357.00 |