GIT2 Antibody (27): sc-135926
- GIT2 Antibody (27) is a mouse monoclonal IgG1, cited in 1 publications, provided at 50 µg/0.5 ml
- raised against amino acids 1-471 corresponding to the short isoform of GIT2 of human origin
- recommended for detection of the short isoform of GIT2 of mouse, rat, human and canine origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GIT2 Antibody (27). This work is in progress.
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GIT2 Antibody (27) is a mouse monoclonal IgG1 antibody that detects GIT2 in mouse, rat, human, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). GIT2, or GRK-interactor 2, plays a crucial role in the regulation of G protein-coupled receptor signaling by acting as a GTPase-activating protein for members of the ADP ribosylation factor family, which are essential for vesicular trafficking. GIT2 helps modulate the internalization and resensitization of receptors, thereby influencing cellular responses to external signals. Notably, GIT2 interacts with various proteins, including GIT1, which can impact the dynamics of receptor signaling pathways. By facilitating the inactivation of G protein-coupled receptors, GIT2 ensures that cells can effectively respond to stimuli without becoming overstimulated, highlighting GIT2′s importance in maintaining cellular homeostasis and signaling fidelity. Anti-GIT2 antibody (27) is an invaluable tool for researchers studying the intricacies of G protein signaling and its implications in various physiological and pathological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GIT2 Antibody (27) | sc-135926 | 50 µg/0.5 ml | $316.00 |