Girard′s Reagent P (CAS 1126-58-5)
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Girard′s Reagent P is a versatile oxidizing agent utilized in the field of organic chemistry for the oxidation of primary alcohols to aldehydes and secondary alcohols to ketones. Its effectiveness stems from the stable, positively charged pyridinium ion, which facilitates a more controlled and selective oxidation process compared to other harsher oxidizing agents. This selectivity is particularly advantageous in synthetic chemistry where maintaining the integrity of sensitive molecular frameworks is critical. The reagent′s unique structure enables it to act under milder conditions, thereby reducing the risk of overoxidation and unwanted byproducts, making it an indispensable tool in the synthesis of complex organic compounds. Researchers value Girard′s Reagent P for its efficiency and the clean reaction profiles it produces, which are essential for obtaining high-purity products necessary for further chemical analysis and experimentation.
Girard′s Reagent P (CAS 1126-58-5) References
- Girard's reagent P derivative of beta-Apo-8'-carotenal: a potent photoprotective agent. | Kanofsky, JR. and Sima, PD. 2001. Photochem Photobiol. 73: 349-58. PMID: 11332029
- Identification and quantification of protein carbonylation using light and heavy isotope labeled Girard's P reagent. | Mirzaei, H. and Regnier, F. 2006. J Chromatogr A. 1134: 122-33. PMID: 16996067
- Unique potentiometric detection systems for HPLC determination of some steroids in human urine. | Vissers, B., et al. 2009. J Sep Sci. 32: 167-79. PMID: 19156641
- Quenching of singlet oxygen by a carotenoid-cyclodextrin complex: the importance of aggregate formation. | Kanofsky, JR. and Sima, PD. 2009. Photochem Photobiol. 85: 391-9. PMID: 19161405
- Simplified quantitative glycomics using the stable isotope label Girard's reagent p by electrospray ionization mass spectrometry. | Wang, C., et al. 2014. J Proteome Res. 13: 372-84. PMID: 24274809
- High-sensitivity quantification of glycosphingolipid glycans by ESI-MS utilizing ozonolysis-based release and isotopic Girard's reagent labeling. | Wang, C., et al. 2019. Anal Biochem. 582: 113355. PMID: 31276651
- Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Analysis of Human Milk Neutral and Sialylated Free Oligosaccharides Using Girard's Reagent P On-Target Derivatization. | Gao, X., et al. 2019. J Agric Food Chem. 67: 8958-8966. PMID: 31334644
- On-Tissue Derivatization with Girard's Reagent P Enhances N-Glycan Signals for Formalin-Fixed Paraffin-Embedded Tissue Sections in MALDI Mass Spectrometry Imaging. | Zhang, H., et al. 2020. Anal Chem. 92: 13361-13368. PMID: 32865977
- Improved Ion Mobility Separation and Structural Characterization of Steroids using Derivatization Methods. | Velosa, DC., et al. 2022. J Am Soc Mass Spectrom. 33: 1761-1771. PMID: 35914213
- Development and application of a sensitive phosphonium-hydrazide oligosaccharide labelling reagent in capillary electrophoresis- electrospray ionization- mass spectrometry. | Ma, Q., et al. 2022. J Chromatogr A. 1680: 463409. PMID: 35998551
- Detection of 20 endogenous anabolic steroid esters with Girard's Reagent P derivatization in dried blood spots using UPLC-Q-Orbitrap-MS. | Yuan, Y., et al. 2022. J Chromatogr B Analyt Technol Biomed Life Sci. 1213: 123535. PMID: 36455389
- Human milk whey glycoprotein N-glycans varied greatly among different maternal secretor status. | Wang, X., et al. 2023. Carbohydr Polym. 310: 120728. PMID: 36925253
- Reaction of DNA with Girard's reagent P: kinetics of the reaction and resistance of the product to some nucleases. | Zagrebel'nyi, SN., et al. 1974. Mol Biol. 8: 60-3. PMID: 4372515
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Girard′s Reagent P, 25 g | sc-295008 | 25 g | $185.00 |