GIOT-2 Antibody (3421C3a): sc-81143
- GIOT-2 Antibody (3421C3a) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to an internal region of GIOT-2 of human origin
- recommended for detection of GIOT-2 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GIOT-2 Antibody (3421C3a). This work is in progress.
GIOT-2 Antibody (3421C3a) is a mouse monoclonal IgG1 antibody that detects GIOT-2 in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). GIOT-2, also known as Gonadotropin-inducible transcription repressor 2 or ZNF44, is a 589 amino acid protein belonging to the Krüppel C2H2-type zinc-finger family, characterized by its 16 C2H2-type zinc fingers and a single KRAB domain. This nuclear protein plays a crucial role in transcriptional regulation, particularly in the repression of gonadotropin gene expression, which is vital for maintaining proper reproductive function and hormonal balance. The presence of the KRAB domain is significant as KRAB interacts with KAP1, facilitating the recruitment of histone-modifying proteins that can alter chromatin structure and influence gene expression. Anti-GIOT-2 antibody (3421C3a) enables researchers to gain insights into the regulatory mechanisms of gonadotropin expression and the broader implications for reproductive health and endocrine signaling.
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GIOT-2 Antibody (3421C3a) References:
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GIOT-2 Antibody (3421C3a) | sc-81143 | 100 µg/ml | $339.00 |