Molecular structure of Ginsenoside Rg3, CAS Number: 14197-60-5
Ginsenoside Rg3 (CAS 14197-60-5)
See product citations (1)
Application:
Ginsenoside Rg3 is a steroid glycoside derivative which affects endothelium relaxation in the aorta
CAS Number:
14197-60-5
Molecular Weight:
785.01
Molecular Formula:
C42H72O13
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Ginsenoside Rg3 affects endothelium dependent relaxation in the aorta. Ginsenosides, which are biologically active compounds found in ginseng and other Panax plants, are structurally steroid glycosides derived from squalene, a triterpene. Among them, Ginsenoside Rg3 is a specific panaxadiol present in both white and red P. ginseng. It has demonstrated the ability to induce apoptosis and inhibit angiogenesis in various cancer models. Notably, Ginsenoside Rg3 can be generated through the heating of other ginsenosides, resulting in increased levels in steamed or dried ginseng preparations.
Ginsenoside Rg3 (CAS 14197-60-5) References
- Ginsenoside Rg3 induces DNA damage in human osteosarcoma cells and reduces MNNG-induced DNA damage and apoptosis in normal human cells. | Zhang, YH., et al. 2014. Oncol Rep. 31: 919-25. PMID: 24337872
- Ginsenoside Rg3 enhances islet cell function and attenuates apoptosis in mouse islets. | Kim, SS., et al. 2014. Transplant Proc. 46: 1150-5. PMID: 24815149
- Stereospecificity of ginsenoside Rg3 in the promotion of cellular immunity in hepatoma H22-bearing mice. | Wu, R., et al. 2014. J Food Sci. 79: H1430-5. PMID: 25041540
- Stereoselective skin anti-photoaging properties of ginsenoside Rg3 in UV-B-irradiated keratinocytes. | Lim, CJ., et al. 2014. Biol Pharm Bull. 37: 1583-90. PMID: 25056231
- Synergistic antitumor effect of ginsenoside Rg3 and cisplatin in cisplatin‑resistant bladder tumor cell line. | Lee, YJ., et al. 2014. Oncol Rep. 32: 1803-8. PMID: 25175462
- Ginsenoside Rg3 sensitizes human non-small cell lung cancer cells to γ-radiation by targeting the nuclear factor-κB pathway. | Wang, L., et al. 2015. Mol Med Rep. 12: 609-14. PMID: 25738799
- Ginsenoside Rg3 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell and C57BL/6 mice. | Cho, YS., et al. 2014. Pharmazie. 69: 818-22. PMID: 25985577
- Ginsenoside Rg3 induces apoptosis in human multiple myeloma cells via the activation of Bcl-2-associated X protein. | Luo, Y., et al. 2015. Mol Med Rep. 12: 3557-3562. PMID: 25998024
- Ginsenoside Rg3 regulates S-nitrosylation of the NLRP3 inflammasome via suppression of iNOS. | Yoon, SJ., et al. 2015. Biochem Biophys Res Commun. 463: 1184-9. PMID: 26086107
- 20(S)-ginsenoside Rg3 promotes senescence and apoptosis in gallbladder cancer cells via the p53 pathway. | Zhang, F., et al. 2015. Drug Des Devel Ther. 9: 3969-87. PMID: 26309394
- Ginsenoside Rg3 antagonizes adriamycin-induced cardiotoxicity by improving endothelial dysfunction from oxidative stress via upregulating the Nrf2-ARE pathway through the activation of akt. | Wang, X., et al. 2015. Phytomedicine. 22: 875-84. PMID: 26321736
- Anti-Metastasis Effects of Ginsenoside Rg3 in B16F10 Cells. | Lee, SG., et al. 2015. J Microbiol Biotechnol. 25: 1997-2006. PMID: 26370799
- Ginsenoside Rg3 inhibits colon cancer cell migration by suppressing nuclear factor kappa B activity. | Junmin, S., et al. 2015. J Tradit Chin Med. 35: 440-4. PMID: 26427115
- Kinetic study for the optimization of ginsenoside Rg3 production by heat treatment of ginsenoside Rb1. | Vo, HT., et al. 2015. J Ginseng Res. 39: 304-13. PMID: 26869822
Inhibitor of:
CYP26A1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ginsenoside Rg3, 5 mg | sc-204767 | 5 mg | $202.00 | |||
Ginsenoside Rg3, 10 mg | sc-204767A | 10 mg | $340.00 |