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Ginsenoside Rb1 (CAS 41753-43-9)

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Application:
Ginsenoside Rb1 is an antiproliferative agent
CAS Number:
41753-43-9
Purity:
≥98%
Molecular Weight:
1109.29
Molecular Formula:
C54H92O23
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ginsenoside Rb1 is part of a class of steroid glycosides, and triterpene saponins that can be found in the plant genus Panax (ginseng). Ginsenoside Rb1 appears to be most abundant in Panax quinquefolius (American Ginseng). Ginsenoside Rb1 is a type of saponin, a class of compounds known for their surfactant properties. The compound may have properties that inhibit the growth of tumors.


Ginsenoside Rb1 (CAS 41753-43-9) References

  1. Ginsenoside Rb1 and mitochondria: A short review of the literature.  |  Zhou, P., et al. 2019. Mol Cell Probes. 43: 1-5. PMID: 30529056
  2. Ginsenoside Rb1 ameliorates CKD-associated vascular calcification by inhibiting the Wnt/β-catenin pathway.  |  Zhou, P., et al. 2019. J Cell Mol Med. 23: 7088-7098. PMID: 31423730
  3. Ginsenoside Rb1 reduces H2O2‑induced HUVEC dysfunction by stimulating the sirtuin‑1/AMP‑activated protein kinase pathway.  |  Zheng, Z., et al. 2020. Mol Med Rep. 22: 247-256. PMID: 32377712
  4. Ginsenoside Rb1 ameliorates autophagy via the AMPK/mTOR pathway in renal tubular epithelial cells in vitro and in vivo.  |  Liu, X., et al. 2020. Int J Biol Macromol. 163: 996-1009. PMID: 32659400
  5. Ginsenoside Rb1 ameliorates cardiotoxicity triggered by aconitine via inhibiting calcium overload and pyroptosis.  |  Wang, M., et al. 2021. Phytomedicine. 83: 153468. PMID: 33513559
  6. Berberine and Ginsenoside Rb1 Ameliorate Depression-Like Behavior in Diabetic Rats.  |  Zhang, JH., et al. 2021. Am J Chin Med. 49: 1195-1213. PMID: 34049474
  7. Ginsenoside Rb1 prevents lipopolysaccharide-induced depressive-like behavior by inhibiting inflammation and neural dysfunction and F2 elicits a novel antidepressant-like effect: A metabolite-based network pharmacology study.  |  Liang, W., et al. 2022. J Ethnopharmacol. 282: 114655. PMID: 34537284
  8. Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.  |  Lu, J., et al. 2021. J Food Sci. 86: 5503-5515. PMID: 34812491
  9. The osteogenesis of Ginsenoside Rb1 incorporated silk/micro-nano hydroxyapatite/sodium alginate composite scaffolds for calvarial defect.  |  Wu, Y., et al. 2022. Int J Oral Sci. 14: 10. PMID: 35153297
  10. Ginsenoside Rb1 inhibits oxidative stress-induced ovarian granulosa cell injury through Akt-FoxO1 interaction.  |  Zhou, P., et al. 2022. Sci China Life Sci. 65: 2301-2315. PMID: 35661967
  11. Ginsenoside Rb1 prevents osteoporosis via the AHR/PRELP/NF-κB signaling axis.  |  Zhang, D., et al. 2022. Phytomedicine. 104: 154205. PMID: 35716470
  12. Ginsenoside Rb1 from Panax ginseng attenuates monoiodoacetate-induced osteoarthritis by inhibiting miR-21-5p/FGF18-mediated inflammation.  |  Luan, J., et al. 2022. J Food Biochem. 46: e14340. PMID: 35866931
  13. Ginsenoside CK, rather than Rb1, possesses potential chemopreventive activities in human gastric cancer via regulating PI3K/AKT/NF-κB signal pathway.  |  Wan, Y., et al. 2022. Front Pharmacol. 13: 977539. PMID: 36249752

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ginsenoside Rb1, 5 mg

sc-204765
5 mg
$403.00

Ginsenoside Rb1, 10 mg

sc-204765A
10 mg
$683.00

What is the appearance of the chemical?

Asked by: two2igm05
Thank you for your question. Ginsenoside Rb1, sc-204765, is a white powder.
Answered by: TechService7
Date published: 2017-01-20
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Rated 5 out of 5 by from Yu et alYu et al. (PubMed ID 26199550) found that ginsenoside Rb1 increased insulin sensitivity and alleviated hepatic fat accumulation in obese diabetic mice. -SCBT Publication Review
Date published: 2015-01-13
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Ginsenoside Rb1 is rated 5.0 out of 5 by 1.
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