Molecular structure of Gingerenone A, CAS Number: 128700-97-0
Gingerenone A (CAS 128700-97-0)
See product citations (2)
Alternate Names:
(E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-4-hepten-3-one
CAS Number:
128700-97-0
Molecular Weight:
356.41
Molecular Formula:
C21H24O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Gingerenone A is a diarylheptanoid found in Z. officinale (ginger). Gingerenone A belongs to a class of compounds called gingerols. It contains antifungal and antiparasitic properties. As an antioxidant, gingerenone A can help protect against oxidative stress by neutralizing free radicals, molecules that can cause cellular damage. From an agricultural perspective, understanding the biosynthesis of compounds like gingerenone A in ginger plants can inform breeding and cultivation practices aimed at enhancing the phytochemical content of ginger. This could lead to the production of ginger varieties with optimized levels of specific compounds.
Gingerenone A (CAS 128700-97-0) References
- [Phenolic and amide constituents from Lycianthes marlipoensis]. | Guo, F. and Li, Y. 2011. Zhongguo Zhong Yao Za Zhi. 36: 2507-10. PMID: 22256755
- Anthelmintic constituents from ginger (Zingiber officinale) against Hymenolepis nana. | Lin, RJ., et al. 2014. Acta Trop. 140: 50-60. PMID: 25063389
- Identification of a Dual Inhibitor of Janus Kinase 2 (JAK2) and p70 Ribosomal S6 Kinase1 (S6K1) Pathways. | Byun, S., et al. 2015. J Biol Chem. 290: 23553-62. PMID: 26242912
- MS-Based Metabolite Profiling of Aboveground and Root Components of Zingiber mioga and Officinale. | Han, JS., et al. 2015. Molecules. 20: 16170-85. PMID: 26404226
- Gingerenone A Attenuates Monocyte-Endothelial Adhesion via Suppression of I Kappa B Kinase Phosphorylation. | Kim, HJ., et al. 2018. J Cell Biochem. 119: 260-268. PMID: 28513976
- Gingerenone A, a polyphenol present in ginger, suppresses obesity and adipose tissue inflammation in high-fat diet-fed mice. | Suk, S., et al. 2017. Mol Nutr Food Res. 61: PMID: 28556482
- Ginger (Zingiber officinale) phytochemicals-gingerenone-A and shogaol inhibit SaHPPK: molecular docking, molecular dynamics simulations and in vitro approaches. | Rampogu, S., et al. 2018. Ann Clin Microbiol Antimicrob. 17: 16. PMID: 29609660
- Gingerenone A Sensitizes the Insulin Receptor and Increases Glucose Uptake by Inhibiting the Activity of p70 S6 Kinase. | Chen, J., et al. 2018. Mol Nutr Food Res. 62: e1800709. PMID: 30296358
- In Vitro and In Vivo Antiviral Activity of Gingerenone A on Influenza A Virus Is Mediated by Targeting Janus Kinase 2. | Wang, J., et al. 2020. Viruses. 12: PMID: 33050000
- Inhibition of Escherichia coli ATP synthase by dietary ginger phenolics. | Hughes, T., et al. 2021. Int J Biol Macromol. 182: 2130-2143. PMID: 34087308
- Gingerenone A Induces Antiproliferation and Senescence of Breast Cancer Cells. | Yu, TJ., et al. 2022. Antioxidants (Basel). 11: PMID: 35326237
- Identification of gingerenone A as a novel senolytic compound. | Moaddel, R., et al. 2022. PLoS One. 17: e0266135. PMID: 35349590
- Gingerenone A Alleviates Ferroptosis in Secondary Liver Injury in Colitis Mice via Activating Nrf2-Gpx4 Signaling Pathway. | Chen, Y., et al. 2022. J Agric Food Chem. 70: 12525-12534. PMID: 36135333
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Gingerenone A, 250 mg | sc-490979 | 250 mg | $808.00 |