Molecular structure of Ghrelin (human), CAS Number: 258279-04-8
Ghrelin (human) (CAS 258279-04-8)
See product citations (3)
Alternate Names:
Endogenous GHS-R ligand
Application:
Ghrelin (human) is an endogenous peptide GHS-R agonist
CAS Number:
258279-04-8
Molecular Weight:
3370.86
Molecular Formula:
C149H249N47O42
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ghrelin (human) is an endogenous agonist peptide for the growth hormone secretagogue receptor (GHS-R) and is mainly produced in the stomach.The GHS-R potently stimulates growth hormone release from the pituitary gland in vitro. Ghrelin (human) is an activator of GHS-R1a. The structure of ghrelin includes a notable post-translational modification: the serine residue at the third position is acylated with an octanoic acid. This acylation is essential for its biological activity, particularly its ability to bind to the GHS-R. Upon binding to its receptor, ghrelin promotes fat storage and stimulates the release of growth hormone.
Ghrelin (human) (CAS 258279-04-8) References
- Contractile effects of ghrelin-related peptides on the chicken gastrointestinal tract in vitro. | Kitazawa, T., et al. 2007. Peptides. 28: 617-24. PMID: 17145117
Activator of:
ALS, BMAL1, CART, CYP19, GALP, GH-1, GHRH, GHS-R1a, GLP-2R, GRP, MC3-R, NPY, Ob-R, Pancreatic Icosapeptide, Pancreatic Polypeptide, PDX-1, POMC, QRFP, SP, and SUR-5.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ghrelin (human), 0.5 mg | sc-364689 | 0.5 mg | $182.00 | |||
Ghrelin (human), 1 mg | sc-364689A | 1 mg | $292.00 |