Gγ 5 Antibody (3B8): sc-517161
- Gγ 5 Antibody (3B8) is a mouse monoclonal IgG2a κ Gγ 5 antibody provided at 100 µg/ml
- raised against amino acids 1-68 representing full length Gγ 5 of human origin
- recommended for detection of Gγ 5 of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Gγ 5 Antibody (3B8). This work is in progress.
Gγ 5 Antibody (3B8) is a mouse monoclonal IgG2a kappa light chain antibody that detects the G gamma 5 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-G gamma 5 antibody (3B8) is available as the non-conjugated format. G gamma 5 protein plays a crucial role in the function of heterotrimeric G proteins, which are essential for transmitting signals from cell surface receptors to various intracellular effectors. G proteins help relay information in response to extracellular stimuli, including hormones and neurotransmitters. G gamma 5 subunit interacts with specific G protein alpha and beta subunits, contributing to the formation of distinct G protein complexes that exhibit unique signaling properties. This specificity is vital for regulating diverse cellular responses, as different tissues express varying combinations of G protein subunits, leading to functional diversity in signaling pathways. Understanding G gamma 5 interactions and regulatory mechanisms is essential for elucidating its role in health and disease, making G gamma 5 (3B8) antibody a valuable tool for researchers studying G protein signaling dynamics.
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Gγ 5 Antibody (3B8) References:
- Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes. | Hurowitz, EH., et al. 2000. DNA Res. 7: 111-20. PMID: 10819326
- Different beta-subunits determine G-protein interaction with transmembrane receptors. | Kleuss, C., et al. 1992. Nature. 358: 424-6. PMID: 1322501
- Activation of cytosolic phosphoinositide phospholipase C by G-protein beta gamma subunits. | Blank, JL., et al. 1992. J Biol Chem. 267: 23069-75. PMID: 1331076
- Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA. | von Weizsäcker, E., et al. 1992. Biochem Biophys Res Commun. 183: 350-6. PMID: 1543505
- Diversity of G proteins in signal transduction. | Simon, MI., et al. 1991. Science. 252: 802-8. PMID: 1902986
- G protein diversity is increased by associations with a variety of gamma subunits. | Gautam, N., et al. 1990. Proc Natl Acad Sci U S A. 87: 7973-7. PMID: 2122451
- Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human. | Blatt, C., et al. 1988. Proc Natl Acad Sci U S A. 85: 7642-6. PMID: 2902634
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Gγ 5 Antibody (3B8) | sc-517161 | 100 µg/ml | $322.00 |