GGA2 Antibody (27): sc-135922
- GGA2 Antibody (27) is a mouse monoclonal IgG1 provided at 50 µg/500 µl
- raised against amino acids 334-445 of GGA2 of human origin
- recommended for detection of GGA2 of human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GGA2 Antibody (27). This work is in progress.
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GGA2 Antibody (27) is a mouse monoclonal IgG1 antibody that detects GGA2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). GGA2, a member of the Golgi-localized, γ-adaptin ear-containing, ARF-binding protein family, plays a crucial role in the intracellular trafficking of proteins between the trans-Golgi network and lysosomes, which is essential for maintaining cellular homeostasis and proper protein sorting. Notably, GGA2 is highly expressed in tissues such as the kidney, muscle, and heart, indicating potential tissue-specific functions. GGA2′s structure includes a VHS domain that is vital for binding to the cation-independent mannose 6-phosphate receptor (CI-MPR), facilitating the targeting of lysosomal enzymes. This interaction underscores GGA2′s importance in lysosomal enzyme trafficking, which is critical for various cellular processes, including degradation and recycling of cellular components. Anti-GGA2 antibody (27) is an invaluable tool for researchers studying protein trafficking mechanisms and the functional implications of GGA2 in human health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GGA2 Antibody (27) | sc-135922 | 50 µg/500 µl | $322.00 |