GFAP Antibody (1.BB.807): sc-71143
- GFAP Antibody (1.BB.807) is a mouse monoclonal IgG2b, cited in 10 publications, provided at 100 µg/ml
- raised against purified glial fibrillary acidic protein from human brain
- recommended for detection of 43-45 kDa fragment of GFAP of mouse, rat and human origin by WB, IP and IF
- See GFAP (2E1): sc-33673 for GFAP antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for GFAP Antibody (1.BB.807). This work is in progress.
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GFAP Antibody (1.BB.807) is a mouse monoclonal IgG2b antibody specifically designed to detect glial fibrillary acidic protein (GFAP), an essential intermediate filament protein in astroglial cells of the central nervous system. Raised against purified human brain GFAP, anti-GFAP antibody (1.BB.807) reliably recognizes GFAP from mouse, rat, and human species, making anti-GFAP antibody (1.BB.807) ideal for applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). GFAP is composed of an amino-terminal head domain, a central rod domain, and a carboxy-terminal tail domain, which are crucial for assembly into a stable cytoskeletal network. This structure allows GFAP to interact with proteins like vimentin, nestin, alphaB-crystallin, and plectin, facilitating cellular processes such as maintaining cell shape, intracellular transport, and response to injury. These interactions are vital for astrocyte function and resilience, particularly during astrogliosis, a response to neurological damage characterized by increased GFAP expression. GFAP monoclonal antibody (1.BB.807) is an invaluable tool for researchers investigating the molecular mechanisms of neural health and diseases, providing insights into the role of GFAP and its interacting partners in maintaining the integrity of the central nervous system.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GFAP Antibody (1.BB.807) | sc-71143 | 100 µg/ml | $316.00 |