Molecular structure of Gestodene, CAS Number: 60282-87-3
Gestodene (CAS 60282-87-3)
Application:
Gestodene is a progesterone-like gestogen compound
CAS Number:
60282-87-3
Purity:
≥98%
Molecular Weight:
310.43
Molecular Formula:
C21H26O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Gestodene is a progestogen that functions as a progestin. It acts by binding to and activating the progesterone receptor, leading to the suppression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release from the pituitary gland. This, in turn, inhibits ovulation and prevents the development of the endometrium, creating an unfavorable environment for implantation. Gestodene also thickens the cervical mucus, making it difficult for sperm to penetrate the uterus. At the molecular level, gestodene modulates gene transcription, leading to changes in the endometrial lining and cervical mucus.
Gestodene (CAS 60282-87-3) References
- The new era in oral contraception: pills containing gestodene, norgestimate, and desogestrel. | London, RS. 1992. Obstet Gynecol Surv. 47: 777-82. PMID: 1436906
- Pharmacokinetics of gestodene and ethinyl estradiol after oral administration of a monophasic contraceptive. | Täuber, U., et al. 1990. Am J Obstet Gynecol. 163: 1414-20. PMID: 2220966
- Combined oral contraceptives: venous thrombosis. | de Bastos, M., et al. 2014. Cochrane Database Syst Rev. CD010813. PMID: 24590565
- Clinical aspects of three new progestogens: desogestrel, gestodene, and norgestimate. | Chez, RA. 1989. Am J Obstet Gynecol. 160: 1296-300. PMID: 2524163
- Gestodene: a novel synthetic progestin--characterization of binding to receptor and serum proteins. | Pollow, K., et al. 1989. Contraception. 40: 325-41. PMID: 2548807
- Progestins in preventive hormone therapy. Including pharmacology of the new progestins, desogestrel, norgestimate, and gestodene: are there advantages? | Sobel, NB. 1994. Obstet Gynecol Clin North Am. 21: 299-319. PMID: 7936546
- New progestins--clinical experiences: gestodene. | Shoupe, D. 1994. Am J Obstet Gynecol. 170: 1562-8. PMID: 8178907
- Desogestrel, norgestimate, and gestodene: the newer progestins. | Kaplan, B. 1995. Ann Pharmacother. 29: 736-42. PMID: 8520092
- Gestodene. A review of its pharmacology, efficacy and tolerability in combined contraceptive preparations. | Wilde, MI. and Balfour, JA. 1995. Drugs. 50: 364-95. PMID: 8521763
- Gestodene-containing contraceptives. | Kuhl, H., et al. 1995. Clin Obstet Gynecol. 38: 829-40. PMID: 8616979
- Pharmacokinetics of the new progestogens and influence of gestodene and desogestrel on ethinylestradiol metabolism. | Stanczyk, FZ. 1997. Contraception. 55: 273-82. PMID: 9220223
- [Experience with gestodene-containing hormonal contraceptive]. | Szabó, L., et al. 1998. Orv Hetil. 139: 481-5. PMID: 9528290
- Effects on hemostatic variables of desogestrel- and gestodene-containing oral contraceptives in comparison with levonorgestrel-containing oral contraceptives: a review. | Winkler, UH. 1998. Am J Obstet Gynecol. 179: S51-61. PMID: 9753311
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Gestodene, 10 mg | sc-211560 | 10 mg | $191.00 |