Date published: 2026-5-1

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Genz 644282 (CAS 529488-28-6)

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Alternate Names:
Genz-644282; Genz644282
Application:
Genz 644282 is A Topo I (topoisomerase I) inhibitor
CAS Number:
529488-28-6
Molecular Weight:
407.42
Molecular Formula:
C22H21N3O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Genz 644282 is a Topo I (topoisomerase I) inhibitor with an IC50 value of 0.4 nM in human bone marrow CFU-GM assay. The compound is a cytotoxic agent and shows activity in several human tumor cell lines.


Genz 644282 (CAS 529488-28-6) References

L.S. Kurtzberg et al. Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment. Clin. Cancer Res. 2011, 17, 2777-2787.

P.J. Houghton et al. Testing of the topoisomerase 1 inhibitor Genz-644282 by the pediatric preclinical testing program. Pediatr. Blood Cancer. 2012, 58, 200-209.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Genz 644282, 5 mg

sc-396035
5 mg
$155.00