Gentamicin Antibody (102): sc-57742

Gentamicin Antibody (102) is a mouse monoclonal IgG2a antibody that detects Gentamicin with species reactivity in non-species restricted (NSR) samples through enzyme-linked immunosorbent assay (ELISA). Gentamicin is an aminoglycoside antibiotic derived from the bacterium Micromonospora purpurea, and plays a crucial role in combating various bacterial infections, particularly those caused by Gram-negative bacteria. Anti-Gentamicin antibody (102) binds to the bacterial 30S ribosomal subunit, which not only inhibits the translocation of peptidyl-tRNA from the A-site to the P-site but also leads to misreading of the genetic code. This disruption in protein synthesis prevents bacteria from producing essential proteins necessary for growth and survival. Gentamicin′s unique property of remaining active even after autoclaving makes this antibiotic one of the few heat-stable options, allowing effective utilization in preparing specific microbiological growth media. Gentamicin monoclonal antibody (102) serves as an invaluable tool for researchers studying pharmacodynamics and therapeutic applications, providing insights into efficacy and interactions in various biological contexts.