Molecular structure of Genkwanin, CAS Number: 437-64-9
Genkwanin (CAS 437-64-9)
See product citations (2)
Alternate Names:
4′,5-Dihydroxy-7-methoxyflavone
CAS Number:
437-64-9
Purity:
≥97%
Molecular Weight:
284.26
Molecular Formula:
C16H12O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Genkwanin, a flavonoid compound found in certain plants, is notable in research for its implications in plant defense and UV protection strategies, offering insights into plant resilience to environmental stresses. In biochemistry, it is utilized to dissect flavonoid biosynthetic pathways, helping to delineate the enzymatic processes that underpin plant metabolism. Environmental scientists use genkwanin to monitor plant health and stress responses, making it a natural bioindicator in ecological studies. Additionally, its photoprotective properties are harnessed in materials science to explore its application in dye-sensitized solar cells, representing a convergence of natural product research and renewable energy technology.
Genkwanin (CAS 437-64-9) References
- Determination of genkwanin in rat plasma by liquid chromatography-tandem mass spectrometry: application to a bioavailability study. | Song, Y., et al. 2013. J Pharm Biomed Anal. 84: 129-34. PMID: 23831487
- STUDIES ON A SIMPLE AND EFFICIENT METHOD FOR LARGE-SCALE PREPARATION OF GENKWANIN FROM DAPHNE GENKWA SIEB. ET ZUCC. USING NORMAL-PHASE FLASH CHROMATOGRAPHY. | Shu, Y., et al. 2014. J Liq Chromatogr Relat Technol. 37: 773-785. PMID: 24489458
- Intestinal absorptive transport of Genkwanin from Flos genkwa using a single-pass intestinal perfusion rat model. | Jiang, CP., et al. 2014. Am J Chin Med. 42: 349-59. PMID: 24707867
- Genkwanin inhibits proinflammatory mediators mainly through the regulation of miR-101/MKP-1/MAPK pathway in LPS-activated macrophages. | Gao, Y., et al. 2014. PLoS One. 9: e96741. PMID: 24800851
- Biosynthesis of Two Flavones, Apigenin and Genkwanin, in Escherichia coli. | Lee, H., et al. 2015. J Microbiol Biotechnol. 25: 1442-8. PMID: 25975614
- Antitumor and immunomodulatory activity of genkwanin on colorectal cancer in the APC(Min/+) mice. | Wang, X., et al. 2015. Int Immunopharmacol. 29: 701-707. PMID: 26388189
- Effect of apigenin-7-glucoside, genkwanin and naringenin on tyrosinase activity and melanin synthesis in B16F10 melanoma cells. | Nasr Bouzaiene, N., et al. 2016. Life Sci. 144: 80-5. PMID: 26656314
- Genkwanin nanosuspensions: a novel and potential antitumor drug in breast carcinoma therapy. | Li, Y., et al. 2017. Drug Deliv. 24: 1491-1500. PMID: 28961040
- Inhibition of African swine fever virus infection by genkwanin. | Hakobyan, A., et al. 2019. Antiviral Res. 167: 78-82. PMID: 30991087
- Genkwanin ameliorates adjuvant-induced arthritis in rats through inhibiting JAK/STAT and NF-κB signaling pathways. | Bao, Y., et al. 2019. Phytomedicine. 63: 153036. PMID: 31401534
- Genkwanin suppresses MPP+-induced cytotoxicity by inhibiting TLR4/MyD88/NLRP3 inflammasome pathway in a cellular model of Parkinson's disease. | Li, Q., et al. 2021. Neurotoxicology. 87: 62-69. PMID: 34481870
- Genkwanin Alleviates Mitochondrial Dysfunction and Oxidative Stress in a Murine Model of Experimental Colitis: The Participation of Sirt1. | Chen, Z., et al. 2022. Ann Clin Lab Sci. 52: 301-313. PMID: 35414509
- Genkwanin Prevents Lipopolysaccharide-Induced Inflammatory Bone Destruction and Ovariectomy-Induced Bone Loss. | Fu, X., et al. 2022. Front Nutr. 9: 921037. PMID: 35811983
- Regioselective Glucuronidation of Flavones at C5, C7, and C4' Positions in Human Liver and Intestinal Microsomes: Comparison among Apigenin, Acacetin, and Genkwanin. | Hanioka, N., et al. 2022. Biol Pharm Bull. 45: 1116-1123. PMID: 35908893
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Genkwanin, 10 mg | sc-211559 | 10 mg | $143.00 | |||
Genkwanin, 25 mg | sc-211559A | 25 mg | $235.00 | |||
Genkwanin, 100 mg | sc-211559B | 100 mg | $296.00 | |||
Genkwanin, 250 mg | sc-211559C | 250 mg | $653.00 | |||
Genkwanin, 1 g | sc-211559D | 1 g | $2040.00 |