Molecular structure of GEA 5024, CAS Number: 144575-27-9
GEA 5024 (CAS 144575-27-9)
Alternate Names:
5-Amino-3-(3-chloro-2-methylphenyl)-1,2,3,4-oxatriazolium chloride
Application:
GEA 5024 is a stable, water-soluble nitric oxide donor
CAS Number:
144575-27-9
Purity:
≥97%
Molecular Weight:
247.08
Molecular Formula:
C8H7ClN4O•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
GEA 5024 is a stable, water-soluble nitric oxide donor.
GEA 5024 (CAS 144575-27-9) References
- Involvement of excitatory amino acid receptors and nitric oxide in the rostral ventromedial medulla in modulating secondary hyperalgesia produced by mustard oil. | Urban, MO., et al. 1999. Pain. 81: 45-55. PMID: 10353492
- Supraspinal contributions to hyperalgesia. | Urban, MO. and Gebhart, GF. 1999. Proc Natl Acad Sci U S A. 96: 7687-92. PMID: 10393881
- Sodium nitroprusside-induced mitochondrial apoptotic events in insulin-secreting RINm5F cells are associated with MAP kinases activation. | Bernabé, JC., et al. 2001. Exp Cell Res. 269: 222-9. PMID: 11570814
- The effect of nitric oxide on glucose metabolism. | Ragoobirsingh, D., et al. 2004. Mol Cell Biochem. 263: 29-34. PMID: 15524165
- Cortical feedback to the thalamus is selectively enhanced by nitric oxide. | Alexander, GM., et al. 2006. Neuroscience. 142: 223-34. PMID: 16876956
- The effect of the nitric oxide donor sodium nitroprusside on glucose uptake in human primary skeletal muscle cells. | Henstridge, DC., et al. 2009. Nitric Oxide. 21: 126-31. PMID: 19567271
- Inhibition by nitric oxide-donors of human polymorphonuclear leucocyte functions. | Moilanen, E., et al. 1993. Br J Pharmacol. 109: 852-8. PMID: 8395300
- Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2. | Xie, K., et al. 1997. Oncogene. 15: 771-9. PMID: 9266963
- Expression of nitric oxide synthase in skeletal muscle: a novel role for nitric oxide as a modulator of insulin action. | Kapur, S., et al. 1997. Diabetes. 46: 1691-700. PMID: 9356014
- Investigation of the role of nitric oxide and cyclic GMP in both the activation and inhibition of human neutrophils. | Wanikiat, P., et al. 1997. Br J Pharmacol. 122: 1135-45. PMID: 9401778
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GEA 5024, 10 mg | sc-203056 | 10 mg | $65.00 | |||
GEA 5024, 50 mg | sc-203056A | 50 mg | $180.00 |