Date published: 2026-4-30

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Ganglioside GD3 disodium salt (CAS 62010-37-1)

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Alternate Names:
Disialoganglioside GD3 2Na; GD3 2Na
Application:
Ganglioside GD3 disodium salt is an inducer of mitochondrial permeability
CAS Number:
62010-37-1
Purity:
≥98%
Molecular Weight:
1516.8
Molecular Formula:
C70H123N3O292Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ganglioside GD3 disodium salt (bovine brain) is a molecule that functions as a cell surface receptor and signaling molecule in experimental applications. It plays a role in cell adhesion, migration, and proliferation. Ganglioside Gd3 Disodium Salt (Bovine Brain) interacts with specific proteins and lipids on the cell membrane, modulating intracellular signaling pathways involved in cell growth and differentiation. Ganglioside GD3 disodium salt (bovine brain) is known to influence the activity of various kinases and phosphatases, impacting the regulation of gene expression and cellular responses to external stimuli. At the molecular level, Ganglioside GD3 disodium salt (bovine brain) can affect the organization and dynamics of lipid rafts, which in turn influence the localization and activity of membrane-associated proteins. Its mechanism of action involves the modulation of membrane fluidity and the recruitment of signaling molecules to specific subcellular compartments, ultimately influencing cellular behavior and function in experimental applications.


Ganglioside GD3 disodium salt (CAS 62010-37-1) References

  1. GD3 ganglioside and apoptosis.  |  Malisan, F. and Testi, R. 2002. Biochim Biophys Acta. 1585: 179-87. PMID: 12531552
  2. The ganglioside GD3 as the Greek goddess Hecate: several faces turned towards as many directions.  |  Malisan, F. and Testi, R. 2005. IUBMB Life. 57: 477-82. PMID: 16081368
  3. Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics.  |  Tang, FL., et al. 2021. J Neurochem. 156: 819-833. PMID: 32743804
  4. Ganglioside GD3 May Suppress the Functional Activities of Benign Skin T Cells in Cutaneous T-Cell Lymphoma.  |  Kume, M., et al. 2021. Front Immunol. 12: 651048. PMID: 33859643
  5. Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemia.  |  Wang, J., et al. 2021. J Neurochem. 158: 737-752. PMID: 34133773
  6. Ganglioside GD3 regulates neural stem cell quiescence and controls postnatal neurogenesis.  |  Fuchigami, T., et al. 2023. bioRxiv.. PMID: 36993675
  7. Ganglioside GD3 regulates neural stem cell quiescence and controls postnatal neurogenesis.  |  Fuchigami, T., et al. 2024. Glia. 72: 167-183. PMID: 37667994
  8. GD3 ganglioside is a promising therapeutic target for glioma patients.  |  Hein, V., et al. 2024. Neurooncol Adv. 6: vdae038. PMID: 38590763
  9. A reappraisal of ganglioside GD3 expression in the CNS.  |  Goldman, JE. and Reynolds, R. 1996. Glia. 16: 291-5. PMID: 8721669

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ganglioside GD3 disodium salt, 500 µg

sc-202623
500 µg
$275.00

Ganglioside GD3 disodium salt, 1 mg

sc-202623A
1 mg
$398.00

Ganglioside GD3 disodium salt, 10 mg

sc-202623B
10 mg
$2958.00

Ganglioside GD3 disodium salt, 50 mg

sc-202623C
50 mg
$13770.00