Molecular structure of γ-Tocotrienol, CAS Number: 14101-61-2
γ-Tocotrienol (CAS 14101-61-2)
See product citations (2)
Alternate Names:
plastochromanol 8
Application:
γ-Tocotrienol is an antioxidant
CAS Number:
14101-61-2
Purity:
>98%
Molecular Weight:
410.63
Molecular Formula:
C28H42O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
γ-Tocotrienol is found in high concentrations in palm oil and rice bran and recent studies have shown that tocotrienols may be more effective antioxidants than α-tocopherol, the most abundant form of vitamin E. Spontaneously hypertensive rats fed a diet which includes γ-tocotrienol show significant reduction of systolic blood pressure and an increase of nitric oxide synthase activity in blood vessels. γ-Tocotrienol at 20muM induces apoptosis of malignant sympathoadrenal (+SA) murine mammary epithelial cells.
γ-Tocotrienol (CAS 14101-61-2) References
- Tocotrienol suppresses adipocyte differentiation and Akt phosphorylation in 3T3-L1 preadipocytes. | Uto-Kondo, H., et al. 2009. J Nutr. 139: 51-7. PMID: 19056650
- Complexation of tocotrienol with gamma-cyclodextrin enhances intestinal absorption of tocotrienol in rats. | Ikeda, S., et al. 2010. Biosci Biotechnol Biochem. 74: 1452-7. PMID: 20622447
- γ-Tocotrienol induces paraptosis-like cell death in human colon carcinoma SW620 cells. | Zhang, JS., et al. 2013. PLoS One. 8: e57779. PMID: 23469066
- γ-Tocotrienol-induced autophagy in malignant mammary cancer cells. | Tiwari, RV., et al. 2014. Exp Biol Med (Maywood). 239: 33-44. PMID: 24231340
- γ-Tocotrienol reduces human airway smooth muscle cell proliferation and migration. | Harada, T., et al. 2015. Pulm Pharmacol Ther. 32: 45-52. PMID: 25956071
- γ-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status. | Singh, VK. and Hauer-Jensen, M. 2016. Int J Mol Sci. 17: PMID: 27153057
- γ-Tocotrienol but not γ-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents. | Kannappan, R., et al. 2016. J Biol Chem. 291: 16922. PMID: 27496963
- γ-Tocotrienol Inhibits TGF-β1-Induced Contractile Phenotype Expression of Human Airway Smooth Muscle Cells. | Fukushima, T., et al. 2017. Yonago Acta Med. 60: 16-23. PMID: 28331417
- Tocotrienols as an Anti-Breast Cancer Agent. | Trujillo, M., et al. 2021. Antioxidants (Basel). 10: PMID: 34573015
- γ-Tocotrienol inhibits T helper 17 cell differentiation via the IL-6/JAK/STAT3 signaling pathway. | Zhao, H., et al. 2022. Mol Immunol. 151: 126-133. PMID: 36126500
- Transcriptomic Analysis of the Anticancer Effects of Annatto Tocotrienol, Delta-Tocotrienol and Gamma-Tocotrienol on Chondrosarcoma Cells. | Pang, KL., et al. 2022. Nutrients. 14: PMID: 36296960
- Gamma-Tocotrienol Modulates Total-Body Irradiation-Induced Hematopoietic Injury in a Nonhuman Primate Model. | Garg, TK., et al. 2022. Int J Mol Sci. 23: PMID: 36555814
- γ-tocotrienol regulates gastric cancer by targeting notch signaling pathway. | Xie, L. and Yan, J. 2023. Hereditas. 160: 15. PMID: 37055846
Inhibitor of:
TRADD.Activator of:
NF-E2, and OGG1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
γ-Tocotrienol, 1 mg | sc-205529 | 1 mg | $48.00 | |||
γ-Tocotrienol, 10 mg | sc-205529A | 10 mg | $349.00 |