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γ-D-Glutamylaminomethylsulfonic acid (CAS 90237-02-8)

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Alternate Names:
GAMS
Application:
γ-D-Glutamylaminomethylsulfonic acid is an GluR (AMPA/kainate recepetor) inhibitor
CAS Number:
90237-02-8
Molecular Weight:
240.23
Molecular Formula:
C6H12N2O6S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Gamma-D-Glutamylaminomethylsulfonic acid is involved in the regulation of cellular processes through its function as a key intermediate in the biosynthesis of certain peptides and proteins. It acts as a component in the formation of specific molecular structures, contributing to the stability and functionality of these biomolecules. At the molecular level, it participates in the transfer of amino acid residues during the synthesis of peptides, thereby influencing the composition and properties of the resulting macromolecules. Its mode of action involves facilitating the incorporation of building blocks into the growing peptide chains, ultimately influencing the conformation and activity of the final protein products. Gamma-D-Glutamylaminomethylsulfonic acid plays a significant role in the molecular pathways that govern the assembly and modification of biologically active molecules, contributing to the complexity and functionality of cellular processes.


γ-D-Glutamylaminomethylsulfonic acid (CAS 90237-02-8) References

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  2. Effects of glutamate receptor agonists on the p13 auditory evoked potential and startle response in the rat.  |  Simon, C., et al. 2011. Front Neurol. 2: 3. PMID: 21441978
  3. Identification of agents that reduce renal hypoxia-reoxygenation injury using cell-based screening: purine nucleosides are alternative energy sources in LLC-PK1 cells during hypoxia.  |  Szoleczky, P., et al. 2012. Arch Biochem Biophys. 517: 53-70. PMID: 22100704
  4. Complex interaction between quisqualate and kainate receptors as revealed by measurement of GABA release from striatal neurons in primary culture.  |  Pin, JP., et al. 1989. Eur J Pharmacol. 172: 81-91. PMID: 2541001
  5. Pharmacological aspects of excitatory synaptic transmission to second-order vestibular neurons in the frog.  |  Cochran, SL., et al. 1987. Synapse. 1: 102-23. PMID: 2850617
  6. Kynurenic acid and gamma-D-glutamylaminomethylsulfonic acid suppress the compound action potential of the auditory nerve.  |  Bobbin, RP. and Ceasar, G. 1987. Hear Res. 25: 77-81. PMID: 2879824
  7. Preferential block of desensitizing AMPA receptor in hippocampal neurons by gamma-D-glutamylaminomethylsulfonic acid.  |  Wilsch, VW., et al. 1995. Eur J Pharmacol. 284: 141-7. PMID: 8549618

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

γ-D-Glutamylaminomethylsulfonic acid, 1 mg

sc-295005
1 mg
$90.00

γ-D-Glutamylaminomethylsulfonic acid, 5 mg

sc-295005A
5 mg
$300.00