Gal1-β-4GlcNAc-β-Bn (CAS 53167-38-7)

Gal1-β-4GlcNAc-β-Bn, also known as benzyl β-D-galactopyranosyl-(1→4)-β-D-N-acetylglucosamine, is a key intermediate in the synthesis of complex oligosaccharides and glycoconjugates. Its chemical structure consists of a galactose residue linked to a N-acetylglucosamine moiety via a β-glycosidic linkage, with a benzyl protecting group attached to the anomeric carbon of the galactose unit. This compound is widely utilized in carbohydrate chemistry research for its role as a building block in the assembly of biologically relevant glycans and glycoconjugates. Chemists leverage its strategic reactivity and selectivity in glycosylation reactions to introduce galactose residues into oligosaccharide chains with precise control over stereochemistry. Furthermore, Gal1-β-4GlcNAc-β-Bn serves as a valuable substrate for enzymatic glycosylation reactions, enabling the chemoenzymatic synthesis of complex carbohydrates and glycoconjugates with high efficiency and specificity. Researchers exploit its synthetic versatility to access structurally diverse glycoconjugates, mimicking natural glycan structures and investigating their roles in various biological processes. Additionally, this compound finds applications in glycobiology, glycomics, and glycoengineering, providing insights into carbohydrate-protein interactions, cell signaling pathways, and immune responses. Overall, Gal1-β-4GlcNAc-β-Bn plays a crucial role in advancing research in carbohydrate chemistry and glycobiology, facilitating the development of novel glycotherapeutics, vaccines, and biomaterials.