Molecular structure of Gadolinium(III) chloride, CAS Number: 10138-52-0
Gadolinium(III) chloride (CAS 10138-52-0)
See product citations (4)
Alternate Names:
Gadolinium trichloride
Application:
Gadolinium(III) chloride is a source of Gd3+ ion
CAS Number:
10138-52-0
Purity:
≥99%
Molecular Weight:
263.61
Molecular Formula:
GdCl3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Gadolinium(III) chloride is a preparation of the metal Gadolinium which is employed in various applications. Gadolinium(III) chloride provides a source of the Gd3+ ion which is described to be a mechanosensitive Ca2+ channel blocker, and the perpendicular orientation of human primary dermal fibroblasts was shown to be blocked by introduction of Gadolinium(III) chloride. The coronary vasodilation effects of the sesquiterpene compound Vulgarenol, suggested to involve inducible nitric oxide synthase (NOS) and endothelial NOS overexpression, was antagonized by Gadolinium(III) chloride. Another study investigating decreased coronary vascular resistance imparted by Viscum album aqueous extract suggested a mechanism involving overexpression of NOS-2 and NOS-3, and Gadolinium(III) chloride was also used to antagonize this effect.
Gadolinium(III) chloride (CAS 10138-52-0) References
- An ion pair uniting a gadolinium(III)-Schiff base complex and uranyl tetrachloride. | Pons Y Moll, O., et al. 2001. Acta Crystallogr C. 57: 392-3. PMID: 11313570
- Mechanical stress activates the nuclear factor-kappaB pathway in skeletal muscle fibers: a possible role in Duchenne muscular dystrophy. | Kumar, A. and Boriek, AM. 2003. FASEB J. 17: 386-96. PMID: 12631578
- Loss of dystrophin causes aberrant mechanotransduction in skeletal muscle fibers. | Kumar, A., et al. 2004. FASEB J. 18: 102-13. PMID: 14718391
- Role of macrophages in host resistance to group A streptococci. | Goldmann, O., et al. 2004. Infect Immun. 72: 2956-63. PMID: 15102808
- Intracellular signaling specificity in response to uniaxial vs. multiaxial stretch: implications for mechanotransduction. | Hornberger, TA., et al. 2005. Am J Physiol Cell Physiol. 288: C185-94. PMID: 15371259
- Kupffer cells and macrophages are not required for hepatic hepcidin activation during iron overload. | Montosi, G., et al. 2005. Hepatology. 41: 545-52. PMID: 15726660
- Viscum album aqueous extract induces NOS-2 and NOS-3 overexpression in Guinea pig hearts. | Tenorio-Lopez, FA., et al. 2006. Nat Prod Res. 20: 1176-82. PMID: 17127505
- Vulgarenol, a sesquiterpene isolated from Magnolia grandiflora, induces nitric oxide synthases II and III overexpression in guinea pig hearts. | del Valle-Mondragón, L., et al. 2007. Z Naturforsch C J Biosci. 62: 725-30. PMID: 18069247
- Distinct mechanosensitive Ca2+ influx mechanisms in human primary synovial fibroblasts. | Sakamoto, Y., et al. 2010. J Orthop Res. 28: 859-64. PMID: 20108315
- Antagonism of RNase L Is Required for Murine Coronavirus Replication in Kupffer Cells and Liver Sinusoidal Endothelial Cells but Not in Hepatocytes. | Li, Y. and Weiss, SR. 2016. J Virol. 90: 9826-9832. PMID: 27558415
- Hypotonic stress promotes ATP release, reactive oxygen species production and cell proliferation via TRPV4 activation in rheumatoid arthritis rat synovial fibroblasts. | Hu, F., et al. 2017. Biochem Biophys Res Commun. 486: 108-115. PMID: 28274876
- Modifying the Surface of Silica Nanoparticles with Amino or Carboxyl Groups Decreases Their Cytotoxicity to Parenchymal Hepatocytes. | Nagano, T., et al. 2017. Biol Pharm Bull. 40: 726-728. PMID: 28458361
- Ionic association and electron spin relaxation rates in aquo gadolinium (III) complexes. | Sur, SK. and Bryant, RG. 1996. J Magn Reson B. 111: 105-8. PMID: 8661268
Inhibitor of:
2610021K21Rik, 6330403A02Rik, ASIC3, BSPII, C18orf30, C18orf58, CCDC109B, CCDC90A, connexin 25, connexin 32, connexin 33, connexin 40.1, connexin 45, CRISP-4, EG631584, Ferrochelatase, Grpa, GSDML, LRRC8B, LRRC8E, mucolipin 1, NELL1, Orai3, PCDHB3, Polycystin-L2, SLC41A3, TMEM150C, TMEM63A, TMEM63C, Triadin, Troponin C, Trp4, V1RG4, V1RG5, V1RG6, V1RH2, V1RH4, VCAC3, and VILIP-3.Activator of:
6330403A02Rik, Enkurin, MS4A4C, OTOP1, OTOP3, TMC4, and VRL-1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Gadolinium(III) chloride, 5 g | sc-224004 | 5 g | $153.00 | |||
Gadolinium(III) chloride, 25 g | sc-224004A | 25 g | $357.00 |