Gabapentin-d4 (CAS 1185039-20-6)
See product citations (1)
QUICK LINKS
Gabapentin-d4 is a deuterated analog of gabapentin, where four hydrogen atoms are replaced with deuterium. This modified version is particularly useful in analytical chemistry, where it serves as an internal standard for mass spectrometry-based assays to ensure accurate quantification of gabapentin in various samples due to its almost identical chemical properties, but distinct mass. In neurobiological research, Gabapentin-d4 aids in understanding the compound′s mechanism of action, such as its interaction with voltage-gated calcium channels. It allows for the tracing of gabapentin′s absorption, distribution, metabolism, and excretion within biological systems without interference from the endogenous compound.
Gabapentin-d4 (CAS 1185039-20-6) References
- Gas chromatography-electron ionization-mass spectrometry quantitation of valproic acid and gabapentin, using dried plasma spots, for therapeutic drug monitoring in in-home medical care. | Ikeda, K., et al. 2014. Biomed Chromatogr. 28: 1756-62. PMID: 24889681
- PHARMACOKINETIC PROPERTIES OF A SINGLE ADMINISTRATION OF ORAL GABAPENTIN IN THE GREAT HORNED OWL (BUBO VIRGINIANUS). | Yaw, TJ., et al. 2015. J Zoo Wildl Med. 46: 547-52. PMID: 26352959
- Multi-kinetics and site-specific release of gabapentin and flurbiprofen from oral fixed-dose combination: in vitro release and in vivo food effect. | Sonvico, F., et al. 2017. J Control Release. 262: 296-304. PMID: 28774840
- Development and clinical applications of the dried blood spot method for therapeutic drug monitoring of anti-epileptic drugs. | Min, KL., et al. 2019. Basic Clin Pharmacol Toxicol. 125: 215-236. PMID: 31199557
- Investigations on dose proportionality and drug-drug interaction for a fixed-dose combination of trazodone and gabapentin. | Ruggieri, A., et al. 2021. Int J Clin Pharmacol Ther. 59: 71-86. PMID: 33040841
- Analytical Considerations When Developing an LC-MS/MS Method for More than 30 Analytes. | Enders, JR., et al. 2018. J Appl Lab Med. 2: 543-554. PMID: 33636886
- An innovative biofilter technology for reducing environmental spreading of emerging pollutants and odour emissions during municipal sewage treatment. | De Sanctis, M., et al. 2022. Sci Total Environ. 803: 149966. PMID: 34481161
- Alterations in Excitatory and Inhibitory Synaptic Development Within the Mesolimbic Dopamine Pathway in a Mouse Model of Prenatal Drug Exposure. | Boggess, T., et al. 2021. Front Pediatr. 9: 794544. PMID: 34966707
- From data to reliable conclusions: Identification and comparison of persistent micropollutants and transformation products in 37 wastewater samples by non-target screening prioritization. | Tisler, S., et al. 2022. Water Res. 219: 118599. PMID: 35598471
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Gabapentin-d4, 1 mg | sc-218553 | 1 mg | $347.00 | |||
Gabapentin-d4, 10 mg | sc-218553A | 10 mg | $2448.00 |