FXR1/2 Antibody (C-5): sc-166433

FXR1/2 Antibody (C-5) is a mouse monoclonal IgG3 kappa light chain antibody that detects FXR1/2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-FXR1/2 antibody (C-5) is available as the non-conjugated form. FXR1 and FXR2 proteins play crucial roles in mRNA metabolism regulation and are particularly important in fragile X syndrome, the most common form of inherited intellectual disability, which arises from FMR1 gene silencing on the X chromosome. FXR1 and FXR2 proteins interact with FMR1 protein (FMRP), forming heterodimers essential for specific mRNAs transport and translation. FXR1, FXR2, and FMRP interaction is vital for synaptic plasticity and neuronal function, highlighting significance in cognitive processes. FXR1 and FXR2 are involved in cellular stress response and have been implicated in various neurodevelopmental disorders. Nuclear and cytoplasmic localization of FXR1 and FXR2 underscores multifaceted roles in gene expression regulation and mRNA transport, making FXR1/2 (C-5) monoclonal antibody an invaluable tool for researchers studying these critical pathways in neurobiology and disease.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FXR1/2 Antibody (C-5) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-FXR1/2 Antibody (C-5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FXR1/2 Antibody (C-5) Specifications

Alternate Product Name: FXR1/2

Product Clone Name: C-5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃ kappa light chain

Amino Acids: 526-557

Epitope Target: FXR1

Epitope Species: human

Product Reactivity/Detection: FXR1 and FXR2

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: equine, canine, bovine and porcine

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₃ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for FXR1/2 Antibody (C-5): P: Blocking Peptide

The preferred FXR1 antibody is FXR1 Antibody (B-2): sc-374148.