Fusarenon X (CAS 23255-69-8)
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Fusarenon X is a mycotoxin that is found in certain species of Fusarium fungi, which are studied for their impact on agricultural commodities. This compound is of interest in food safety and toxicology research, where it is often evaluated for its contamination effects on crops such as cereals and grains. In the laboratory, fusarenon X is used to understand the molecular mechanisms of mycotoxin-induced cytotoxicity and genotoxicity in cellular models. Research involving fusarenon X also includes the development of detection methods, such as chromatography and spectroscopy, to identify and quantify this toxin in foodstuffs. Additionally, studies focus on the metabolic pathways through which fusarenon X is biotransformed by both plants and animals, which is essential for assessing the risks associated with exposure to this mycotoxin.
Fusarenon X (CAS 23255-69-8) References
- Fusarenon-X induced apoptosis in HL-60 cells depends on caspase activation and cytochrome c release. | Miura, K., et al. 2002. Toxicology. 172: 103-12. PMID: 11882350
- The fates of trichothecene mycotoxins, nivalenol and fusarenon-X, in mice. | Poapolathep, A., et al. 2003. Toxicon. 41: 1047-54. PMID: 12875880
- Fate of fusarenon-X in broilers and ducks. | Poapolathep, A., et al. 2008. Poult Sci. 87: 1510-5. PMID: 18648042
- Comparison of murine anorectic responses to the 8-ketotrichothecenes 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, fusarenon X and nivalenol. | Wu, W., et al. 2012. Food Chem Toxicol. 50: 2056-61. PMID: 22465835
- Toxicokinetics and tissue depletion of Fusarenon-X and its metabolite nivalenol in piglets. | Saengtienchai, T., et al. 2014. Food Chem Toxicol. 66: 307-12. PMID: 24508584
- Oral exposure of fusarenon-X induced apoptosis in Peyer's patches, thymus, and spleen of mice. | Aupanun, S., et al. 2015. Res Vet Sci. 102: 217-22. PMID: 26412547
- Fusarenon-X-induced apoptosis in the liver, kidney, and spleen of mice. | Sutjarit, S. and Poapolathep, A. 2016. J Toxicol Pathol. 29: 207-11. PMID: 27559248
- Studies on mechanisms of diarrhea induced by fusarenon-X, a trichothecene mycotoxin from Fusarium species: fusarenon-X-induced diarrhea is not mediated by cyclic nucleotides. | Matsuoka, Y. and Kubota, K. 1987. Toxicol Appl Pharmacol. 91: 326-32. PMID: 2827346
- Toxicokinetic profile of fusarenon-X and its metabolite nivalenol in the goat (Capra hircus). | Phruksawan, W., et al. 2018. Toxicon. 153: 78-84. PMID: 30172791
- Individual and combined mycotoxins deoxynivalenol, nivalenol, and fusarenon-X induced apoptosis in lymphoid tissues of mice after oral exposure. | Aupanun, S., et al. 2019. Toxicon. 165: 83-94. PMID: 31054920
- Anorexic action of fusarenon-x in the hypothalamus and intestine. | Tominaga, M., et al. 2020. Toxicon. 187: 57-64. PMID: 32882257
- Genotoxicity of Fusarium mycotoxins (nivalenol, fusarenon-X, T-2 toxin, and zearalenone) in Chinese hamster V79-E cells in vitro. | Thust, R., et al. 1983. Arch Geschwulstforsch. 53: 9-15. PMID: 6222715
- Studies on mechanisms of diarrhea induced by fusarenon-X, a trichothecene mycotoxin from Fusarium species; characteristics of increased intestinal absorption rate induced by fusarenon-X. | Matsuoka, Y. and Kubota, K. 1982. J Pharmacobiodyn. 5: 193-9. PMID: 7097487
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fusarenon X, 1 mg | sc-235234 | 1 mg | $401.00 |