FUS/TLS Antibody (15): sc-135911
- FUS/TLS Antibody (15) is a mouse monoclonal IgG1, cited in 2 publications, provided at 50 µg/0.5 ml
- raised against amino acids 2-117 of FUS/TLS of human origin
- recommended for detection of FUS/TLS of mouse, rat and human origin by WB, IP and IF
- See FUS/TLS (4H11): sc-47711 for FUS/TLS antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for FUS/TLS Antibody (15). This work is in progress.
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SEE ALSO...
FUS/TLS Antibody (15) is a mouse monoclonal IgG1 antibody that detects FUS/TLS in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). FUS/TLS is a crucial nuclear RNA-binding protein that plays a significant role in the regulation of gene expression and RNA processing. FUS/TLS (15) antibody can help detect interactions with various nuclear steroid receptors, suggesting FUS/TLS involvement in the transcriptional response to hormonal signals, which is vital for maintaining cellular homeostasis and responding to environmental changes. Additionally, anti-FUS/TLS antibody (15) can identify FUS/TLS as part of the TFIID complex, indicating involvement in the initiation of transcription and processing of primary transcripts. The dysregulation of FUS/TLS, often due to chromosomal translocations, can lead to oncogenic fusions that contribute to the development of certain cancers, such as myxoid liposarcomas and myeloid leukemias. FUS/TLS monoclonal antibody (15) enables researchers to gain insights into the functional dynamics of FUS/TLS and its implications in both normal physiology and disease states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FUS/TLS Antibody (15) | sc-135911 | 50 µg/0.5 ml | $322.00 |