Furylfuramide (CAS 3688-53-7)
QUICK LINKS
Furylfuramide, a synthetic nitrofuran analog, is mainly utilized in scientific research for its mutagenic properties, serving as a model compound in genetic toxicology studies. Its incorporation into experimental designs helps in understanding the mechanisms of DNA damage and mutation, as well as the cellular processes that are triggered in response to such damage. Researchers study the interaction between furylfuramide and various cellular enzymes involved in DNA repair and replication to elucidate the pathways that contribute to genomic stability. In the field of environmental mutagenesis, the effects of furylfuramide on different organisms are assessed to determine the potential risks of environmental exposure to similar compounds. Additionally, it is used as a reference substance in the development and calibration of new assays and techniques for detecting mutagenic activity in substances, including the Ames test.
Furylfuramide (CAS 3688-53-7) References
- Moscatilin from Dendrobium nobile, a naturally occurring bibenzyl compound with potential antimutagenic activity. | Miyazawa, M., et al. 1999. J Agric Food Chem. 47: 2163-7. PMID: 10552513
- Antimutagenic activity of flavonoids from Pogostemon cablin. | Miyazawa, M., et al. 2000. J Agric Food Chem. 48: 642-7. PMID: 10725128
- Antimutagenic activity of isoflavone from Pueraria lobata. | Miyazawa, M., et al. 2001. J Agric Food Chem. 49: 336-41. PMID: 11170596
- Mutagenic activity of furylfuramide on cultured mouse cells. | Umeda, M., et al. 1975. Jpn J Exp Med. 45: 161-70. PMID: 1237041
- Antimutagenic activity of flavonoids from Chrysanthemum morifolium. | Miyazawa, M. and Hisama, M. 2003. Biosci Biotechnol Biochem. 67: 2091-9. PMID: 14586095
- Suppression of mutagens-induced SOS response by phytoncide solution using Salmonella typhimurium TA1535/pSK1002 umu test. | Hisama, M., et al. 2008. J Oleo Sci. 57: 381-90. PMID: 18536507
- Suppression of SOS-inducing activity of chemical mutagens by metabolites from microbial transformation of (+)-longicyclene. | Sakata, K. and Miyazawa, M. 2010. J Agric Food Chem. 58: 9001-5. PMID: 20662538
- Metabolic deactivation of furylfuramide by cytochrome P450 in human and rat liver microsomes. | Shimada, T., et al. 1990. Carcinogenesis. 11: 103-10. PMID: 2403855
- Toxicological significance of hepatic responses to furylfuramide(AF-2) in the rat. | Fukuhara, M., et al. 1986. Toxicology. 39: 165-76. PMID: 3010505
- Mutagenic and recombinogenic activities of the food additive furylfuramide in eurkaryotes. | Ong, TM. and Shahin, MM. 1974. Science. 184: 1086-7. PMID: 4283384
- The effect of simultaneous and alternate feeding of furylfuramide and 4-dimethylaminoazobenzene on rats. | Miyaji, T. 1971. Tohoku J Exp Med. 103: 371-9. PMID: 4327060
- Acute and chronic toxicity of furylfuramide in rats and mice. | Miyaji, T. 1971. Tohoku J Exp Med. 103: 331-69. PMID: 5284035
- Effect of furylfuramide on reproduction and malformation. | Miyaji, T. 1971. Tohoku J Exp Med. 103: 381-8. PMID: 5560195
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Furylfuramide, 10 mg | sc-489518 | 10 mg | $398.00 |