Date published: 2026-4-25

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Furan-3-ylethynyltrimethylsilane (CAS 465521-19-1)

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Alternate Names:
(3-Furylethynyl)trimethylsilane
CAS Number:
465521-19-1
Purity:
≥95%
Molecular Weight:
164.28
Molecular Formula:
C9H12OSi
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Furan-3-ylethynyltrimethylsilane functions as a reactive intermediate in organic synthesis, participating in various chemical reactions to form new carbon-carbon or carbon-heteroatom bonds. Its mechanism of action involves the activation of the alkyne group, allowing it to undergo coupling reactions with other organic molecules. Furan-3-Ylethynyltrimethylsilane can serve as a building block for the construction of complex organic compounds, enabling the formation of diverse molecular structures through its participation in cross-coupling reactions. Furan-3-ylethynyltrimethylsilane′s mechanism of action involves its ability to undergo nucleophilic addition and subsequent rearrangement, leading to the formation of new carbon-carbon bonds. Furan-3-Ylethynyltrimethylsilane′s functional role lies in its capacity to facilitate the synthesis of novel organic molecules with potential applications in materials science, chemical biology, and related fields.


Furan-3-ylethynyltrimethylsilane (CAS 465521-19-1) References

  1. Synthesis of 2,3-disubstituted indenones by cobalt-catalyzed [3+2] annulation of o-methoxycarbonylphenylboronic acid with alkynes.  |  Ueda, M., et al. 2016. Chem Commun (Camb). 52: 13237-13240. PMID: 27768149
  2. Stereoselective Formal Hydroamidation of Si-Substituted Arylacetylenes with DIBAL-H and Isocyanates: Synthesis of (E)- and (Z)-α-Silyl-α,β-unsaturated Amides.  |  Lee, H., et al. 2020. J Org Chem. 85: 12024-12035. PMID: 32909750

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Furan-3-ylethynyltrimethylsilane, 1 g

sc-235223
1 g
$36.00