Fumigaclavine A (CAS 6879-59-0)
See product citations (1)
QUICK LINKS
Fumigaclavine A, an ergot alkaloid and mycotoxin, is a polyketide natural product found in the fungus Fusarium moniliforme. It belongs to the fumigaclavine compound family, which comprises secondary metabolites produced by fungi. Extensive research has focused on Fumigaclavine A (FCA) due to its potential applications in biotechnology and agriculture. Fumigaclavine A exhibits a broad spectrum of biological activities, including antifungal, antibacterial, and anti-inflammatory properties in vitro. Moreover, Fumigaclavine A has shown potential as an insecticide and fungicide in agricultural settings. Although the precise mechanism of action for Fumigaclavine A remains incompletely understood, it is believed to hinder the growth of fungi and bacteria by disrupting their cell membranes, leading to cell death.
Fumigaclavine A (CAS 6879-59-0) References
- Reverse prenyltransferase in the biosynthesis of fumigaclavine C in Aspergillus fumigatus: gene expression, purification, and characterization of fumigaclavine C synthase FGAPT1. | Unsöld, IA. and Li, SM. 2006. Chembiochem. 7: 158-64. PMID: 16397874
- [Clavine alkaloid biosynthesis by the fungus Penicillium palitans westling 1911 isolated from ancient permafrost deposits]. | Kozlovskiĭ, AG., et al. 2009. Prikl Biokhim Mikrobiol. 45: 202-6. PMID: 19382708
- Multi-mycotoxin analysis of maize silage by LC-MS/MS. | Rasmussen, RR., et al. 2010. Anal Bioanal Chem. 397: 765-76. PMID: 20213172
- Chemotypic and genotypic diversity in the ergot alkaloid pathway of Aspergillus fumigatus. | Robinson, SL. and Panaccione, DG. 2012. Mycologia. 104: 804-12. PMID: 22453123
- Production, detection, and purification of clavine-type ergot alkaloids. | Wallwey, C. and Li, SM. 2012. Methods Mol Biol. 944: 121-31. PMID: 23065612
- Production and characterization of antibodies against fumigaclavine A. | Latif, H., et al. 2009. Mycotoxin Res. 25: 159-64. PMID: 23605095
- Fumigaclavines D-H, new ergot alkaloids from endophytic Aspergillus fumigatus. | Xu, J., et al. 2014. Planta Med. 80: 1131-7. PMID: 25127024
- Comparison of diagnostic tools for the detection of aspergillosis in blood samples of experimentally infected falcons. | Fischer, D., et al. 2014. Avian Dis. 58: 587-98. PMID: 25619004
- Immunochemical analysis of fumigaclavine mycotoxins in respiratory tissues and in blood serum of birds with confirmed aspergillosis. | Latif, H., et al. 2015. Mycotoxin Res. 31: 177-83. PMID: 26388046
- Characterization of the putative polysaccharide synthase CpsA and its effects on the virulence of the human pathogen Aspergillus fumigatus. | Nepal, B., et al. 2019. PLoS One. 14: e0216092. PMID: 31026268
- Mycotoxins produced by Aspergillus fumigatus isolated from silage. | Cole, RJ., et al. 1977. Ann Nutr Aliment. 31: 685-91. PMID: 350117
- Production of fumigaclavine A by Aspergillus tamarii Kita. | Janardhanan, KK., et al. 1984. Can J Microbiol. 30: 247-50. PMID: 6713307
- Reclassification of the Penicillium roqueforti group into three species on the basis of molecular genetic and biochemical profiles. | Boysen, M., et al. 1996. Microbiology (Reading). 142 (Pt 3): 541-549. PMID: 8868429
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fumigaclavine A, 1 mg | sc-203051 | 1 mg | $230.00 | |||
Fumigaclavine A, 5 mg | sc-203051A | 5 mg | $954.00 |