Fumaric acid monomethyl ester-d3 (CAS 2756-87-8 (unlabeled))

Fumaric acid monomethyl ester-d3 is a stable isotope-labeled variant of fumaric acid monomethyl ester, where three hydrogen atoms are replaced with deuterium. This labeling increases the molecular mass and alters the vibrational modes of the molecule, making it particularly useful in analytical applications like nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry. These techniques benefit from the distinct signals and reduced background interference that deuterium provides, allowing for more precise and detailed chemical analysis. Fumaric acid monomethyl ester itself is a derivative of fumaric acid, an intermediate in the citric acid cycle that is crucial for cellular respiration in eukaryotic organisms. The esterified form, which includes a methoxy group, is often used in biochemical studies to investigate the metabolism of fumaric acid and its derivatives, as well as their roles in various biological pathways. The use of the deuterium-labeled version, Fumaric acid monomethyl ester-d3, aids in these studies by enabling researchers to track and quantify the molecule′s incorporation and transformation within biological systems more accurately.