Molecular structure of Fucosterol, CAS Number: 17605-67-3
Fucosterol (CAS 17605-67-3)
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Alternate Names:
5-CHOLESTEN-24(28)-ETHYLIDENE-3β-OL
Application:
Fucosterol is a steroid for proteomics research
CAS Number:
17605-67-3
Purity:
≥98%
Molecular Weight:
412.69
Molecular Formula:
C29H48O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Fucosterol is a sterol compound that is frequently employed in various research applications, mainly those concerning marine biology and the study of algal biochemistry. In nutritional studies, fucosterol is investigated for its potential impact on the lipid profiles of marine organisms. It is also used as a biomarker to assess the presence and concentration of certain algae in marine samples, due to its prevalence within those species. In ecological studies, researchers analyze fucosterol content to understand the role of sterols in the marine ecosystem, including how they contribute to the structure and function of cell membranes in aquatic organisms. Additionally, fucosterol serves as a reference compound for chromatographic and spectrometric analyses aimed at identifying and quantifying sterols in complex environmental samples.
Fucosterol (CAS 17605-67-3) References
- Fucosterol isolated from Undaria pinnatifida inhibits lipopolysaccharide-induced production of nitric oxide and pro-inflammatory cytokines via the inactivation of nuclear factor-κB and p38 mitogen-activated protein kinase in RAW264.7 macrophages. | Yoo, MS., et al. 2012. Food Chem. 135: 967-75. PMID: 22953812
- Fucosterol is a selective liver X receptor modulator that regulates the expression of key genes in cholesterol homeostasis in macrophages, hepatocytes, and intestinal cells. | Hoang, MH., et al. 2012. J Agric Food Chem. 60: 11567-75. PMID: 23116181
- Fucosterol attenuates lipopolysaccharide-induced acute lung injury in mice. | Li, Y., et al. 2015. J Surg Res. 195: 515-21. PMID: 25818525
- Fucosterol protects cobalt chloride induced inflammation by the inhibition of hypoxia-inducible factor through PI3K/Akt pathway. | Sun, Z., et al. 2015. Int Immunopharmacol. 29: 642-647. PMID: 26395918
- Fucosterol, a sterol extracted from Sargassum fusiforme, shows antidepressant and anticonvulsant effects. | Zhen, XH., et al. 2015. Eur J Pharmacol. 768: 131-8. PMID: 26515446
- Fucosterol, isolated from Ecklonia stolonifera, inhibits adipogenesis through modulation of FoxO1 pathway in 3T3-L1 adipocytes. | Lee, JH., et al. 2017. J Pharm Pharmacol. 69: 325-333. PMID: 28134973
- Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity. | Mo, W., et al. 2018. Gastroenterol Res Pract. 2018: 2824139. PMID: 30116260
- Fucosterol inhibits adipogenesis through the activation of AMPK and Wnt/β-catenin signaling pathways. | Song, Y., et al. 2017. Food Sci Biotechnol. 26: 489-494. PMID: 30263569
- Fucosterol exerts protection against amyloid β-induced neurotoxicity, reduces intracellular levels of amyloid β and enhances the mRNA expression of neuroglobin in amyloid β-induced SH-SY5Y cells. | Gan, SY., et al. 2019. Int J Biol Macromol. 121: 207-213. PMID: 30300695
- Fucosterol from an Edible Brown Alga Ecklonia stolonifera Prevents Soluble Amyloid Beta-Induced Cognitive Dysfunction in Aging Rats. | Oh, JH., et al. 2018. Mar Drugs. 16: PMID: 30301140
- Cytotoxic activity of the seaweed compound fucosterol, alone and in combination with 5-fluorouracil, in colon cells using 2D and 3D culturing. | Ramos, AA., et al. 2019. J Toxicol Environ Health A. 82: 537-549. PMID: 31258008
- Fucosterol from Sargassum horridum as an amyloid-beta (Aβ1-42) aggregation inhibitor: in vitro and in silico studies. | Castro-Silva, ES., et al. 2021. J Biomol Struct Dyn. 39: 1271-1283. PMID: 32159448
- Fucosterol of Marine Macroalgae: Bioactivity, Safety and Toxicity on Organism. | Meinita, MDN., et al. 2021. Mar Drugs. 19: PMID: 34677444
- The pharmacokinetic characteristics and excretion studies of fucosterol from Sargasssum fusiforme in rats. | Wang, P., et al. 2022. Biomed Chromatogr. 36: e5309. PMID: 34981527
- Fucosterol Isolated from Dietary Brown Alga Sargassum horneri Protects TNF-α/IFN-γ-Stimulated Human Dermal Fibroblasts via Regulating Nrf2/HO-1 and NF-κB/MAPK Pathways. | Kirindage, KGIS., et al. 2022. Antioxidants (Basel). 11: PMID: 35892631
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fucosterol, 5 mg | sc-235218 | 5 mg | $169.00 |