FTSJ2 Antibody (2372C6a): sc-81647

FTSJ2 Antibody (2372C6a) is a mouse monoclonal IgG1 antibody that detects FTSJ2 protein of human origin by western blotting (WB) and immunoprecipitation (IP). Anti-FTSJ2 antibody (2372C6a) is available as a non-conjugated format. FTSJ2 protein, also known as putative ribosomal RNA methyltransferase 2, plays a crucial role in modifying ribosomal RNA by methylating uridine residues, which is essential for proper ribosome assembly and function. This methylation process is vital for protein synthesis accuracy, influencing ribosome stability and translation fidelity. FTSJ2 is predominantly located in the nucleus and belongs to the RrmJ family of methyltransferases, which are evolutionarily conserved and involved in various RNA processing events. FTSJ2 gene is situated on chromosome 7p22 and shows abundant expression in skeletal muscle, placenta, and heart, as well as various cancer cell lines, highlighting its potential significance in both normal physiology and disease states.

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FTSJ2 Antibody (2372C6a) References:

1. Mitotic checkpoint locus MAD1L1 maps to human chromosome 7p22 and mouse chromosome 5.  |  Jin, DY., et al. 1999. Genomics. 55: 363-4. PMID: 10049595
2. The FtsJ/RrmJ heat shock protein of Escherichia coli is a 23 S ribosomal RNA methyltransferase.  |  Caldas, T., et al. 2000. J Biol Chem. 275: 16414-9. PMID: 10748051
3. Identification and characterization of FTSJ2, a novel human nucleolar protein homologous to bacterial ribosomal RNA methyltransferase.  |  Ching, YP., et al. 2002. Genomics. 79: 2-6. PMID: 11827451
4. Active site in RrmJ, a heat shock-induced methyltransferase.  |  Hager, J., et al. 2002. J Biol Chem. 277: 41978-86. PMID: 12181314
5. Substrate binding analysis of the 23S rRNA methyltransferase RrmJ.  |  Hager, J., et al. 2004. J Bacteriol. 186: 6634-42. PMID: 15375145
6. Identification and characterization of two putative human arginine methyltransferases (HRMT1L1 and HRMT1L2).  |  Scott, HS., et al. 1998. Genomics. 48: 330-40. PMID: 9545638

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FTSJ2 Antibody (2372C6a) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-FTSJ2 Antibody (2372C6a) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FTSJ2 Antibody (2372C6a) Specifications

Alternate Product Name: FTSJ2

Product Clone Name: 2372C6a

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: FTSJ2

Epitope Species: human

Product Reactivity/Detection: FTSJ2

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 1.0% stabilizer protein

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for FTSJ2 Antibody (2372C6a): N/A