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Fructose-leucine (mixture of diastereomers) (CAS 34393-18-5)

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Alternate Names:
N-(1-Deoxy-D-fructos-1-yl)-L-leucine; (S)-1-[(1-Carboxy-3-methylbutyl)amino]-1-deoxy-D-fructose
CAS Number:
34393-18-5
Molecular Weight:
293.31
Molecular Formula:
C12H23NO7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fructose-leucine (mixture of diastereomers) is composed of two diastereomers, fructose and leucine, which have been studied extensively for their potential applications in scientific research. This mixture is an agonist of the enzymes fructose-1,6-bisphosphatase and fructose-2,6-bisphosphatase. These enzymes are responsible for the breakdown of fructose-1,6-bisphosphate and fructose-2,6-bisphosphate, both important intermediates in glycolysis. Fructose-leucine may act to increase the rate of glycolysis and gluconeogenesis. It also increases the activity of insulin and glucagon, which are hormones that regulate glucose metabolism.


Fructose-leucine (mixture of diastereomers) (CAS 34393-18-5) References

  1. Simultaneous quantification of ten Amadori compounds in tobacco using liquid chromatography with tandem mass spectrometry.  |  Liu, L., et al. 2017. J Sep Sci. 40: 849-857. PMID: 27987265
  2. Nutritional consequences of the Maillard reaction. Amino acid availability from fructose-leucine and fructose-tryptophan in the rat.  |  Sgarbieri, VC., et al. 1973. J Nutr. 103: 657-63. PMID: 4740192
  3. Inhibition of human breast cancer metastasis in nude mice by synthetic glycoamines.  |  Glinsky, GV., et al. 1996. Cancer Res. 56: 5319-24. PMID: 8968076
  4. Purification and Properties of Fructosylamine Oxidase from Aspergillus sp. 1005  |  Tatsuo Horiuchi and Toshiko Kurokawa. 1991. Agricultural and Biological Chemistry. 55: 333–338.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fructose-leucine (mixture of diastereomers), 2.5 mg

sc-470657
2.5 mg
$546.00

Fructose-leucine (mixture of diastereomers), 10 mg

sc-470657A
10 mg
$2024.00

Fructose-leucine (mixture of diastereomers), 25 mg

sc-470657B
25 mg
$4076.00