Molecular structure of Fosphenytoin disodium salt, CAS Number: 92134-98-0
Fosphenytoin disodium salt (CAS 92134-98-0)
Alternate Names:
5,5-Diphenyl-3-[(phosphonooxy)methyl]-2,4-imidazolidinedione disodium salt
CAS Number:
92134-98-0
Purity:
98%
Molecular Weight:
406.24
Molecular Formula:
C16H13N2Na2O6P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Fosphenytoin disodium salt is a water-soluble form of phenytoin, which is used to increase the bioavailability of phenytoin. Fosphenytoin is rapidly converted to phenytoin. Fosphenytoin acts on voltage-gated sodium channels and increases the activity of glutamic acid decarboxylase (GAD), an enzyme involved in the synthesis of GABA. Fosphenytoin disodium salt is utilized in research focused on the properties and mechanisms of phosphorus-containing compounds. Its properties and interactions are of interest in the field of chemical research, particularly in understanding the chemistry of phosphorus derivatives.
Fosphenytoin disodium salt (CAS 92134-98-0) References
- Prodrug/Enzyme based acceleration of absorption of hydrophobic drugs: an in vitro study. | Kapoor, M. and Siegel, RA. 2013. Mol Pharm. 10: 3519-24. PMID: 23937162
- Development and Clinical Application of Phosphorus-Containing Drugs. | Yu, H., et al. 2020. Med Drug Discov. 8: 100063. PMID: 32864606
- Intranasal fosphenytoin: The promise of phosphate esters in nose-to-brain delivery of poorly soluble drugs. | Pires, PC., et al. 2021. Int J Pharm. 592: 120040. PMID: 33157214
- Nose-to-brain delivery of phenytoin and its hydrophilic prodrug fosphenytoin combined in a microemulsion - formulation development and in vivo pharmacokinetics. | Pires, PC., et al. 2021. Eur J Pharm Sci. 164: 105918. PMID: 34174414
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fosphenytoin disodium salt, 1 g | sc-357360 | 1 g | $400.00 | |||
Fosphenytoin disodium salt, 5 g | sc-357360A | 5 g | $1200.00 |