Molecular structure of Fosinoprilat Disodium Salt, CAS Number: 95399-71-6
Fosinoprilat Disodium Salt (CAS 95399-71-6)
Application:
Fosinoprilat Disodium Salt is a metabolite of the ACE inhibitor fosinopril
CAS Number:
95399-71-6
Molecular Weight:
479.46
Molecular Formula:
C23H32NNa2O5P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Fosinoprilat Disodium Salt is a metabolite of Fosinopril, a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor.
Fosinoprilat Disodium Salt (CAS 95399-71-6) References
- Fosinopril/hydrochlorothiazide: single dose and steady-state pharmacokinetics and pharmacodynamics. | O'Grady, P., et al. 1999. Br J Clin Pharmacol. 48: 375-81. PMID: 10510149
- Comparison of the pharmacokinetics of fosinoprilat with enalaprilat and lisinopril in patients with congestive heart failure and chronic renal insufficiency. | Greenbaum, R., et al. 2000. Br J Clin Pharmacol. 49: 23-31. PMID: 10606834
- Liquid chromatography/electrospray tandem mass spectrometry method for the quantitation of fosinoprilat in human serum using automated 96-well solid-phase extraction for sample preparation. | Jemal, M., et al. 2000. Rapid Commun Mass Spectrom. 14: 1023-8. PMID: 10861982
- Fosinopril. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in essential hypertension. | Murdoch, D. and McTavish, D. 1992. Drugs. 43: 123-40. PMID: 1372856
- Development of liquid chromatographic method for fosinoprilat determination in human plasma using microemulsion as eluent. | Jancic, B., et al. 2005. J Chromatogr A. 1088: 187-92. PMID: 16130750
- Development and validation of liquid chromatography-tandem mass spectrometric method for simultaneous determination of fosinopril and its active metabolite fosinoprilat in human plasma. | Cui, S., et al. 2007. J Chromatogr B Analyt Technol Biomed Life Sci. 854: 143-51. PMID: 17482898
- Identification of metabolites of fosinopril produced by human and rat liver microsomes with liquid chromatography-mass spectrometry. | Uutela, P., et al. 2014. Eur J Pharm Sci. 53: 86-94. PMID: 24365260
- Structural basis for the inhibition of human angiotensin-1 converting enzyme by fosinoprilat. | Cozier, GE., et al. 2022. FEBS J. 289: 6659-6671. PMID: 35653492
- Angiotensin-converting enzyme inhibitors: medicinal chemistry and biological actions. | Petrillo, EW. and Ondetti, MA. 1982. Med Res Rev. 2: 1-41. PMID: 6287131
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fosinoprilat Disodium Salt, 5 mg | sc-207700 | 5 mg | $380.00 |