Molecular structure of Fosfomycin Disodium Salt, CAS Number: 26016-99-9
Fosfomycin Disodium Salt (CAS 26016-99-9)
Alternate Names:
Phosphomycin Disodium Salt; Disodium (1R,2S)-(1,2-epoxypropyl)phosphonate
Application:
Fosfomycin Disodium Salt is an antibiotic enzyme inhibitor
CAS Number:
26016-99-9
Molecular Weight:
182.02
Molecular Formula:
C3H5O4P•2Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Fosfomycin Disodium Salt, a chemical compound that holds great promise in the realm of scientific research. This compound, derived from fosfomycin, has captured the attention of researchers in various fields. Fosfomycin Disodium Salt exhibits potent antimicrobial properties, making it useful in the study of bacterial infections and the development of new antibiotics. Researchers have explored its mechanism of action, investigating how it disrupts bacterial cell wall synthesis through inhibition of an essential enzyme. Additionally, Fosfomycin Disodium Salt has shown potential in combating antibiotic-resistant bacteria. Its versatility and efficacy make Fosfomycin Disodium Salt a captivating compound for researchers dedicated to understanding bacterial physiology.
Fosfomycin Disodium Salt (CAS 26016-99-9) References
- Enzymatic synthesis of phosphocarnitine, phosphogabob and fosfomycin. | Wang, K., et al. 2003. Org Biomol Chem. 1: 3564-9. PMID: 14599018
- Capillary electrophoresis analysis of fosfomycin in biological fluids for clinical pharmacokinetic studies. | Petsch, M., et al. 2004. Electrophoresis. 25: 2292-8. PMID: 15274011
- A model for glutathione binding and activation in the fosfomycin resistance protein, FosA. | Rigsby, RE., et al. 2007. Arch Biochem Biophys. 464: 277-83. PMID: 17537395
- In vitro activity of fosfomycin against blaKPC-containing Klebsiella pneumoniae isolates, including those nonsusceptible to tigecycline and/or colistin. | Endimiani, A., et al. 2010. Antimicrob Agents Chemother. 54: 526-9. PMID: 19901089
- In vitro studies on the interaction between human serum albumin and fosfomycin disodium salt, an antibiotic drug by multi-spectroscopic and molecular docking methods. | Meti, MD., et al. 2014. Mol Biol Rep. 41: 2377-87. PMID: 24443227
- Blocking peptidoglycan recycling in Pseudomonas aeruginosa attenuates intrinsic resistance to fosfomycin. | Borisova, M., et al. 2014. Microb Drug Resist. 20: 231-7. PMID: 24819062
- Ion chromatography as highly suitable method for rapid and accurate determination of antibiotic fosfomycin in pharmaceutical wastewater. | Zeng, P., et al. 2014. Water Sci Technol. 69: 2014-22. PMID: 24845315
- Colistin resistance in carbapenemase-producing Klebsiella pneumoniae bloodstream isolates: Evolution over 15 years and temporal association with colistin use by time series analysis. | Tansarli, GS., et al. 2018. Int J Antimicrob Agents. 52: 397-403. PMID: 29960007
- In vitro Activity of Fosfomycin against Multidrug-Resistant Urinary and Nonurinary Gram-Negative Isolates. | Behera, B., et al. 2018. Indian J Crit Care Med. 22: 533-536. PMID: 30111930
- Induction of Melanogenesis by Fosfomycin in B16F10 Cells Through the Upregulation of P-JNK and P-p38 Signaling Pathways. | Ullah, S., et al. 2020. Antibiotics (Basel). 9: PMID: 32290383
- Fosfomycin, Applying Known Methods and Remedies to A New Era. | M, VA., et al. 2020. Diseases. 8: PMID: 32784746
- Fosfomycin and Its Derivatives: New Scale Inhibitors for Oilfield Applications. | Mady, MF. and Ortega, R. 2022. ACS Omega. 7: 10701-10708. PMID: 35382314
- The intriguing biology and chemistry of fosfomycin: the only marketed phosphonate antibiotic. | Cao, Y., et al. 2019. RSC Adv. 9: 42204-42218. PMID: 35548698
- Fosfomycin kinetics after intravenous and oral administration to human volunteers. | Goto, M., et al. 1981. Antimicrob Agents Chemother. 20: 393-7. PMID: 7305325
Inhibitor of:
Enzyme.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fosfomycin Disodium Salt, 1 g | sc-211542 | 1 g | $40.00 | |||
Fosfomycin Disodium Salt, 5 g | sc-211542A | 5 g | $104.00 |