Date published: 2026-4-30

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Formaldehyde-d2 solution (CAS 1664-98-8)

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Alternate Names:
Dideuteriomethanone; Paraformaldehyde-d2
Application:
Formaldehyde-d2 solution is a useful deuterated formaldehyde for proteomics reseach
CAS Number:
1664-98-8
Molecular Weight:
32.04
Molecular Formula:
CD2O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Formaldehyde-d2 solution is a useful deuterated formaldehyde for proteomics reseach. Formaldehyde-d2 solution plays a vital role in various scientific applications. It is employed in the synthesis of dimethylated peptides, contributing to peptide modifications and structural studies. Moreover, this solution is utilized in the quantification of antigens within vaccine products, enabling accurate measurements and assessments. Stable isotope methyl labeling, facilitated by formaldehyde-d2 solution, has significantly advanced antigen quantification in influenza vaccines. Furthermore, it is instrumental in the global quantification of antigens in diverse protein-based vaccines and their manufacturing intermediates, offering valuable insights into vaccine development and quality control processes.


Formaldehyde-d2 solution (CAS 1664-98-8) References

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  2. Enhanced detection of ubiquitin isopeptides using reductive methylation.  |  Chicooree, N., et al. 2013. J Am Soc Mass Spectrom. 24: 421-30. PMID: 23361369
  3. A proteomics analysis to evaluate cytotoxicity in NRK-52E cells caused by unmodified Nano-Fe₃O₄.  |  Lin, YR., et al. 2014. ScientificWorldJournal. 2014: 754721. PMID: 25197711
  4. A bead-based cleavage method for large-scale identification of protease substrates.  |  Wang, C., et al. 2016. Sci Rep. 6: 22645. PMID: 26935269
  5. Activity-Based Sensing for Site-Specific Proteomic Analysis of Cysteine Oxidation.  |  Shi, Y. and Carroll, KS. 2020. Acc Chem Res. 53: 20-31. PMID: 31869209
  6. Combined Omics Approach Identifies Gambogic Acid and Related Xanthones as Covalent Inhibitors of the Serine Palmitoyltransferase Complex.  |  Hoch, DG., et al. 2020. Cell Chem Biol. 27: 586-597.e12. PMID: 32330443
  7. Sample Preparation and Relative Quantitation using Reductive Methylation of Amines for Peptidomics Studies.  |  Correa, CN., et al. 2021. J Vis Exp.. PMID: 34806710
  8. Enabling Global Analysis of Protein Citrullination via Biotin Thiol Tag-Assisted Mass Spectrometry.  |  Shi, Y., et al. 2022. Anal Chem. 94: 17895-17903. PMID: 36512406

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Formaldehyde-d2 solution, 20 g

sc-228228
20 g
$704.00