Date published: 2026-4-24

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Fomesafen (CAS 72178-02-0)

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Alternate Names:
5-[2-Chloro-4-(trifluoromethyl)phenoxy]-N-(methylsulfonyl)-2-nitrobenzamide
CAS Number:
72178-02-0
Purity:
≥97%
Molecular Weight:
438.76
Molecular Formula:
C15H10ClF3N2O6S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fomesafen is a herbicide that functions by inhibiting the enzyme protoporphyrinogen oxidase (PPO). This inhibition leads to the accumulation of toxic compounds within the plant cells, resulting in membrane disruption and ultimately cell death. Fomesafen′s mechanism of action involves the disruption of the electron transport chain in the chloroplasts, leading to the generation of reactive oxygen species and oxidative stress. This oxidative damage interferes with the plant′s ability to photosynthesize and produce energy, ultimately causing plant death. Fomesafen may interfere with the synthesis of carotenoids, which are important pigments for light harvesting and photoprotection in plants. Fomesafen′s mechanism of action disrupts multiple processes in plant cells, leading to its efficacy as a herbicide in experimental applications.


Fomesafen (CAS 72178-02-0) References

  1. Identification, characterization and expression of rice (Oryza sativa) acetyltransferase genes exposed to realistic environmental contamination of mesotrione and fomesafen.  |  Chen, ZJ., et al. 2022. Ecotoxicol Environ Saf. 233: 113349. PMID: 35219957
  2. Exogenous salicylic acid alleviates fomesafen toxicity by improving photosynthetic characteristics and antioxidant defense system in sugar beet.  |  Li, X., et al. 2022. Ecotoxicol Environ Saf. 238: 113587. PMID: 35512468
  3. Phytotoxicity response of sugar beet (Beta vulgaris L.) seedlings to herbicide fomesafen in soil.  |  Li, X., et al. 2022. Ecotoxicol Environ Saf. 239: 113628. PMID: 35576801
  4. Field-Evolved ΔG210-ppo2 from Palmer Amaranth Confers Pre-emergence Tolerance to PPO-Inhibitors in Rice and Arabidopsis.  |  Carvalho-Moore, P., et al. 2022. Genes (Basel). 13: PMID: 35741806
  5. Multiple resistance to ALS-inhibiting and PPO-inhibiting herbicides in Chenopodium album L. from China.  |  Cao, Y., et al. 2022. Pestic Biochem Physiol. 186: 105155. PMID: 35973760
  6. Effect of different soil water managements on the selectivity of fomesafen in conventional and RR soybean.  |  Gonçalves, CG., et al. 2022. J Environ Sci Health B. 57: 786-795. PMID: 36039634
  7. Molecular Mechanisms of Herbicide Resistance in Weeds.  |  Torra, J. and Alcántara-de la Cruz, R. 2022. Genes (Basel). 13: PMID: 36360259
  8. Target gene mutation and enhanced metabolism confer fomesafen resistance in an Amaranthus retroflexus L. population from China.  |  Cao, Y., et al. 2022. Pestic Biochem Physiol. 188: 105256. PMID: 36464361
  9. Development of solid agents of the diphenyl ether herbicide degrading bacterium Bacillus sp. Za based on a mixed organic fertilizer carrier.  |  Zhao, G., et al. 2022. Front Microbiol. 13: 1075930. PMID: 36504824
  10. Research progress on residual characteristics, ecological risk, and abatement of fomesafen in farmland soil.  |  Chen, SS., et al. 2023. Ying Yong Sheng Tai Xue Bao. 34: 815-824. PMID: 37087666
  11. Enhanced Herbicide Metabolism and Target-Site Mutations Confer Multiple Resistance to Fomesafen and Nicosulfuron in Amaranthus retroflexus L.  |  Yang, C., et al. 2023. Biology (Basel). 12: PMID: 37106792
  12. Delivering on sustainable development goals in wastewater reuse for agriculture: Initial prioritization of emerging pollutants in the Tula Valley, Mexico.  |  Garduño-Jiménez, AL., et al. 2023. Water Res. 238: 119903. PMID: 37121200
  13. A New V361A Mutation in Amaranthus palmeri PPX2 Associated with PPO-Inhibiting Herbicide Resistance.  |  Nie, H., et al. 2023. Plants (Basel). 12: PMID: 37176944
  14. A nitroreductase DnrA catalyzes the biotransformation of several diphenyl ether herbicides in Bacillus sp. Za.  |  Tian, Y., et al. 2023. Appl Microbiol Biotechnol.. PMID: 37395748

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fomesafen, 100 mg

sc-235210
100 mg
$101.00