Fmoc-N-methyl-D-allo-isoleucine (CAS 1356090-81-7)
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Fmoc-N-methyl-D-allo-isoleucine is a compound used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a temporary protection for the amino group, allowing for the sequential addition of amino acids without unwanted side reactions. The N-methyl-D-allo-isoleucine residue itself is of interest due to its non-natural structure, which can confer altered conformational properties and biological activity to the peptides it is incorporated into. Researchers utilize this compound to explore the structure-activity relationships in peptides and proteins, and to design novel peptides with specific functions or improved stability compared to their natural counterparts. Additionally, the incorporation of such non-standard amino acids is for creating peptidomimetics—molecules that mimic natural peptides but with enhanced bioavailability, stability, or specificity.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fmoc-N-methyl-D-allo-isoleucine, 250 mg | sc-499076 | 250 mg | $443.00 |