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Fmoc-his(mmt)-oh represents an innovative reagent in the realm of peptide synthesis, offering enhanced efficiency and reliability in the production of peptides. This reagent builds upon the foundation of Fmoc-his-oh, a well-established compound utilized for peptide synthesis over the years. However, Fmoc-his(mmt)-oh distinguishes itself by incorporating a modified side chain expertly linked to the histidine residue, thereby conferring precise control over reaction conditions. The basis of Fmoc-his(mmt)-oh lies in the formation of a covalent bond between the methyl methacrylate side chain and the histidine residue. This covalent bond is skillfully forged through a Michael addition reaction, entailing the introduction of the methyl methacrylate side chain to the histidine residue. As a result, a stable peptide bond emerges, characterized by its resilience against proteolysis and denaturation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fmoc-L-His(Mmt)-OH, 25 g | sc-294904 | 25 g | $406.00 | |||
Fmoc-L-His(Mmt)-OH, 100 g | sc-294904A | 100 g | $908.00 |