Date published: 2026-4-29

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Fmoc-L-Glu(Me)-OH (CAS 145038-50-2)

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Alternate Names:
N-Fmoc-L-glutamic acid gamma-methyl ester
Application:
Fmoc-L-Glu(Me)-OH is a glutamic acid derivative with N-α and side chain protection
CAS Number:
145038-50-2
Purity:
97%
Molecular Weight:
383.39
Molecular Formula:
C21H21NO6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fmoc-L-Glu(Me)-OH, an amino acid derivative, has garnered significant attention in diverse scientific research applications. This compound, characterized as a phenylmethyl ester of glutamic acid, presents itself as a white crystalline solid with water solubility. As a pivotal component for peptide synthesis, Fmoc-L-Glu(Me)-OH has found widespread use in scientific research. The versatility of Fmoc-L-Glu(Me)-OH becomes evident as it plays a role in synthesizing peptides, proteins, and other biomolecules. Moreover, it has proven invaluable in investigating enzyme kinetics, protein structure and function. Additionally, researchers have employed it to delve into the intricate workings of DNA and RNA, unraveling their structure and function. Exploring cellular signaling pathways and designing drugs and other molecular entities are yet more areas where Fmoc-L-Glu(Me)-OH has contributed to scientific inquiry. While the precise mechanism of action of Fmoc-L-Glu(Me)-OH remains partially elusive, it is believed to act as a nucleophile during peptide synthesis, facilitating the formation of peptide bonds between amino acids. Furthermore, this compound is thought to engage in interactions with proteins and other molecules, forming covalent bonds. Additionally, its potential to interact with DNA and RNA, establishing covalent bonds with these genetic materials, provides further avenues for exploration.


Fmoc-L-Glu(Me)-OH (CAS 145038-50-2) References

  1. Ester carbonyl vibration as a sensitive probe of protein local electric field.  |  Pazos, IM., et al. 2014. Angew Chem Int Ed Engl. 53: 6080-4. PMID: 24788907

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fmoc-L-Glu(Me)-OH, 2 g

sc-294895
2 g
$195.00

Fmoc-L-Glu(Me)-OH, 5 g

sc-294895A
5 g
$715.00