Fmoc-Gly-OSu (CAS 113484-74-5)
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Fmoc-Gly-OSu is widely studied in peptide synthesis and proteomics, primarily for its utility as an amino acid derivative in the formation of peptide bonds under mild conditions. This compound is valued for its role in facilitating the introduction of the glycine residue into peptides while providing protection for the amino group through the Fmoc (9-fluorenylmethyloxycarbonyl) group. Research on Fmoc-Gly-OSu includes investigating its reactivity and efficiency in solid-phase peptide synthesis, where it enables the sequential assembly of peptide chains. The stability of Fmoc-Gly-OSu under various synthetic conditions is also a critical focus, ensuring that it maintains its integrity until deprotection is required. Studies further explore the kinetics of its coupling reactions and potential side reactions, which are essential for optimizing synthesis protocols and improving the overall yields of desired peptide products.
Fmoc-Gly-OSu (CAS 113484-74-5) References
- Role of P225 and the C136-C201 disulfide bond in tissue plasminogen activator. | Vindigni, A. and Di Cera, E. 1998. Protein Sci. 7: 1728-37. PMID: 10082369
- Efficient microwave-assisted tandem N- to S-acyl transfer and thioester exchange for the preparation of a glycosylated peptide thioester. | Nagaike, F., et al. 2006. Org Lett. 8: 4465-8. PMID: 16986926
- Colicin M hydrolyses branched lipids II from Gram-positive bacteria. | Patin, D., et al. 2012. Biochimie. 94: 985-90. PMID: 22210388
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fmoc-Gly-OSu, 1 g | sc-294845 | 1 g | $92.00 | |||
Fmoc-Gly-OSu, 2.5 g | sc-294845A | 2.5 g | $100.00 |