Date published: 2025-12-4

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Fmoc-Gly-OH (CAS 29022-11-5)

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Alternate Names:
Fmoc-glycine
Application:
Fmoc-Gly-OH is an Fmoc protected glycine derivative
CAS Number:
29022-11-5
Molecular Weight:
297.31
Molecular Formula:
C17H15NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fmoc-Gly-OH is an Fmoc protected glycine derivative useful for proteomics studies and solid phase peptide synthesis techniques. Glycine is the simplest, and least sterically hindered of the amino acids, which confers a high level of flexibility when incorporated into polypeptides. This compound could be useful for solid phase peptide synthesis and for coupling of saccharide beta-glycosylamines used for the for the fractionation of oligosaccharides and formation of neoglycoconjugates.


Fmoc-Gly-OH (CAS 29022-11-5) References

  1. Heterotrimeric collagen peptides containing functional epitopes. Synthesis of single-stranded collagen type I peptides related to the collagenase cleavage site.  |  Ottl, J., et al. 1999. J Pept Sci. 5: 103-10. PMID: 10100126
  2. 'O-Acyl isopeptide method' for peptide synthesis: Solvent effects in the synthesis of Abeta1-42 isopeptide using 'O-acyl isodipeptide unit'.  |  Taniguchi, A., et al. 2007. J Pept Sci. 13: 868-74. PMID: 17803257
  3. Dicyclopropylmethyl peptide backbone protectant.  |  Carpino, LA., et al. 2009. Org Lett. 11: 3718-21. PMID: 19719204
  4. Rhodamine-marked bombesin: a novel means for prostate cancer fluorescence imaging.  |  Sturzu, A., et al. 2014. Invest New Drugs. 32: 37-46. PMID: 23728918
  5. Honeycomb membranes prepared from 3-O-amino acid functionalized cellulose derivatives.  |  Xu, WZ., et al. 2014. Carbohydr Polym. 100: 126-34. PMID: 24188846
  6. Serine-selective aerobic cleavage of peptides and a protein using a water-soluble copper-organoradical conjugate.  |  Seki, Y., et al. 2014. Angew Chem Int Ed Engl. 53: 6501-5. PMID: 24826926
  7. Efficient Method for the Concentration Determination of Fmoc Groups Incorporated in the Core-Shell Materials by Fmoc-Glycine.  |  Szczepańska, E., et al. 2020. Molecules. 25: PMID: 32882948
  8. Amino-acids condensations in the preparation of N alpha-9-fluorenylmethyloxycarbonylamino-acids with 9-fluorenylmethylchloroformate.  |  Tessier, M., et al. 1983. Int J Pept Protein Res. 22: 125-8. PMID: 6885246
  9. Model studies on protease-catalysed peptide synthesis using 9-fluorenylmethoxycarbonyl protected amino acid derivatives  |  Peter Kuhl, Simone Säuberlich & Hans-Dieter Jakubke. 1992. Monatshefte für Chemie / Chemical Monthly. 123: 1015–1022.
  10. Preservation of the protective group under alkaline conditions by using CaCl2. Applications in peptide synthesis  |  Robert Pascal ∗ 1, Régine Sola. 1998. Tetrahedron Letters. 39: 5031-5034.
  11. Monitoring solid phase reactions with ion-selective electrode  |  Marcel Pátek *, Sylvia Bildstein, Zuzana Flegelová. 1998. Tetrahedron Letters. 39: 753-756.
  12. Oxime Carbonates: Novel Reagents for the Introduction of Fmoc and Alloc Protecting Groups, Free of Side Reactions  |  Sherine N. Khattab, Ramon Subirós-Funosas, Ayman El-Faham, Fernando Albericio. 2010. European Journal of Organic Chemistry. 2010: 3275-3280.
  13. A novel conducting copolymer: Investigation of its matrix properties for cholesterol biosensor applications  |  Saniye Soylemez a, Fulya Ekiz Kanik b, Ayda Goyçek Nurioglu a, Hava Akpinar c, Levent Toppare a b c d. 2013. Sensors and Actuators B: Chemical. 182: 322-329.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fmoc-Gly-OH, 5 g

sc-255183
5 g
$22.00