Date published: 2026-5-30

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Fmoc-D-tyrosine (CAS 112883-29-1)

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Alternate Names:
Fmoc-D-Tyr-OH
Application:
Fmoc-D-tyrosine is an Fmoc protected tyrosine derivative
CAS Number:
112883-29-1
Molecular Weight:
403.6
Molecular Formula:
C24H21NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fmoc-D-tyrosine is an Fmoc protected tyrosine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Tyrosine is a very important amino acid - one of the few amino acids which is phosphorylated to vary the physical properties of the peptides, and is a precursor for the formation of iodinated thyroid hormones. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.


Fmoc-D-tyrosine (CAS 112883-29-1) References

  1. Tyrosine analogues as alternative substrates for protein tyrosine kinase Csk: insights into substrate selectivity and catalytic mechanism.  |  Kim, K., et al. 2000. Bioorg Med Chem. 8: 1263-8. PMID: 10896106
  2. Improved iodine radiolabels for monoclonal antibody therapy.  |  Stein, R., et al. 2003. Cancer Res. 63: 111-8. PMID: 12517786
  3. Vancomycin-Lipopeptide Conjugates with High Antimicrobial Activity on Vancomycin-Resistant Enterococci.  |  Mühlberg, E., et al. 2020. Pharmaceuticals (Basel). 13: PMID: 32485876
  4. Impact of Linker Modification and PEGylation of Vancomycin Conjugates on Structure-Activity Relationships and Pharmacokinetics.  |  Umstätter, F., et al. 2022. Pharmaceuticals (Basel). 15: PMID: 35215272

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fmoc-D-tyrosine, 1 g

sc-294837
1 g
$92.00

Fmoc-D-tyrosine, 5 g

sc-294837A
5 g
$388.00