Date published: 2025-10-17

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Fmoc-D-Tyr(tBu)-OH (CAS 118488-18-9)

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Alternate Names:
Fmoc-O-tert-butyl-D-tyrosine
Application:
Fmoc-D-Tyr(tBu)-OH is an Fmoc protected tyrosine derivative
CAS Number:
118488-18-9
Purity:
≥95%
Molecular Weight:
459.53
Molecular Formula:
C28H29NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fmoc-D-Tyr(tBu)-OH is a protected amino acid derivative employed in the field of peptide synthesis. This compound features an Fmoc (9-fluorenylmethoxycarbonyl) group, which is a standard protecting group for the amine functionality, allowing for its use in solid-phase peptide synthesis (SPPS) techniques. The tBu (tert-butyl) group protects the phenolic hydroxyl of the tyrosine side chain, preventing unwanted side reactions during the elongation of the peptide chain. Researchers use Fmoc-D-Tyr(tBu)-OH to incorporate the D-tyrosine residue into peptides, which is particularly useful in the study of peptide structure-function relationships, stability, and resistance to enzymatic degradation. The incorporation of D-amino acids into peptides is also a strategy for the design of novel peptides with potential biological and industrial applications. Furthermore, this compound is essential in understanding the folding and activity of non-natural peptides, thereby contributing to the broader field of synthetic biology and biophysical research.


Fmoc-D-Tyr(tBu)-OH (CAS 118488-18-9) References

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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fmoc-D-Tyr(tBu)-OH, 1 g

sc-223997
1 g
$41.00