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Fmoc-D-Tyr(tBu)-OH is a protected amino acid derivative employed in the field of peptide synthesis. This compound features an Fmoc (9-fluorenylmethoxycarbonyl) group, which is a standard protecting group for the amine functionality, allowing for its use in solid-phase peptide synthesis (SPPS) techniques. The tBu (tert-butyl) group protects the phenolic hydroxyl of the tyrosine side chain, preventing unwanted side reactions during the elongation of the peptide chain. Researchers use Fmoc-D-Tyr(tBu)-OH to incorporate the D-tyrosine residue into peptides, which is particularly useful in the study of peptide structure-function relationships, stability, and resistance to enzymatic degradation. The incorporation of D-amino acids into peptides is also a strategy for the design of novel peptides with potential biological and industrial applications. Furthermore, this compound is essential in understanding the folding and activity of non-natural peptides, thereby contributing to the broader field of synthetic biology and biophysical research.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fmoc-D-Tyr(tBu)-OH, 1 g | sc-223997 | 1 g | $41.00 |