Date published: 2025-12-4

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Fmoc-Cys(StBu)-OH (CAS 73724-43-3)

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Alternate Names:
Fmoc-S-tert-butylthio-L-cysteine
Application:
Fmoc-Cys(StBu)-OH is an Fmoc protected cysteine derivative
CAS Number:
73724-43-3
Molecular Weight:
431.57
Molecular Formula:
C22H25NO4S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fmoc-Cys(StBu)-OH is an Fmoc protected cysteine derivative potentially useful for proteomics studies, and solid phase peptide synthesis techniques. Cysteine is versatile amino acid involved with many biological processes, including the formation of disulfide bonds - a critical component of protein structure. This compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function.


Fmoc-Cys(StBu)-OH (CAS 73724-43-3) References

  1. DNA display III. Solid-phase organic synthesis on unprotected DNA.  |  Halpin, DR., et al. 2004. PLoS Biol. 2: E175. PMID: 15221029
  2. A viable synthesis of N-methyl cysteine.  |  Ruggles, EL., et al. 2008. Biopolymers. 90: 61-8. PMID: 18008337
  3. Solid-phase synthesis of prenylcysteine analogs.  |  Donelson, JL., et al. 2009. J Org Chem. 74: 2975-81. PMID: 19320430
  4. Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells.  |  Barbuto, S., et al. 2013. Nat Chem Biol. 9: 250-6. PMID: 23416331
  5. Realizing serine/threonine ligation: scope and limitations and mechanistic implication thereof.  |  Wong, CT., et al. 2014. Front Chem. 2: 28. PMID: 24904921
  6. Synthesis of Unprotected Linear or Cyclic O-Acyl Isopeptides in Water Using Bis(2-sulfanylethyl)amido Peptide Ligation.  |  Desmet, R., et al. 2015. Org Lett. 17: 3354-7. PMID: 26075704
  7. Solution-Phase Fmoc-Based Peptide Synthesis for DNA-Encoded Chemical Libraries: Reaction Conditions, Protecting Group Strategies, and Pitfalls.  |  Monty, OBC., et al. 2020. ACS Comb Sci. 22: 833-843. PMID: 33074645
  8. Smaller, Stronger, More Stable: Peptide Variants of a SARS-CoV-2 Neutralizing Miniprotein.  |  Weißenborn, L., et al. 2022. Int J Mol Sci. 23: PMID: 35682988

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fmoc-Cys(StBu)-OH, 1 g

sc-235176
1 g
$85.00