Fmoc-Cys(Dpm)-OH (CAS 247595-29-5)
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Fmoc-Cys(Dpm)-OH functions by temporarily blocking the reactivity of the thiol group, allowing for selective manipulation of other functional groups within the peptide chain. Fmoc-Cys(Dpm)-Oh′s mechanism of action involves the formation of a covalent bond between the Fmoc-Cys(Dpm)-OH molecule and the thiol group of cysteine, effectively masking its reactivity. Fmoc-Cys(Dpm)-OH prevents unwanted side reactions involving the thiol group while enabling the desired chemical transformations to occur at other sites within the peptide sequence. By serving as a temporary shield for the thiol group, Fmoc-Cys(Dpm)-OH facilitates the stepwise assembly of complex peptide structures with precise control over the modification of cysteine residues. Fmoc-Cys(Dpm)-Oh′s specific role in peptide synthesis involves the strategic manipulation of cysteine residues, ensuring the successful construction of custom-designed peptides.
Fmoc-Cys(Dpm)-OH (CAS 247595-29-5) References
- Evaluation of acid-labile S-protecting groups to prevent Cys racemization in Fmoc solid-phase peptide synthesis. | Hibino, H., et al. 2014. J Pept Sci. 20: 30-5. PMID: 24357151
- Investigation on cellular uptake and pharmacodynamics of DOCK2-inhibitory peptides conjugated with cell-penetrating peptides. | Adachi, Y., et al. 2017. Bioorg Med Chem. 25: 2148-2155. PMID: 28284862
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fmoc-Cys(Dpm)-OH, 1 g | sc-327755 | 1 g | $199.00 | |||
Fmoc-Cys(Dpm)-OH, 5 g | sc-327755A | 5 g | $801.00 |