Date published: 2025-12-4

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Fmoc-beta-Ala-OH (CAS 35737-10-1)

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Alternate Names:
N-(9-Fluorenylmethyloxycarbonyl)-beta-alanine
Application:
Fmoc-beta-Ala-OH is an Fmoc protected alanine derivative
CAS Number:
35737-10-1
Molecular Weight:
311.34
Molecular Formula:
C18H17NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fmoc-beta-Ala-OH is an Fmoc protected alanine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Alanine is one of the simplest amino acids - a methyl group as the side chain. This small side chain confers a high degree of flexibility (second only to glycine) when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.


Fmoc-beta-Ala-OH (CAS 35737-10-1) References

  1. Identification of Fmoc-beta-Ala-OH and Fmoc-beta-Ala-amino acid-OH as new impurities in Fmoc-protected amino acid derivatives.  |  Hlebowicz, E., et al. 2005. J Pept Res. 65: 90-7. PMID: 15686539
  2. Formation of Fmoc-beta-alanine during Fmoc-protections with Fmoc-OSu.  |  Obkircher, M., et al. 2008. J Pept Sci. 14: 763-6. PMID: 18219706
  3. Development of lysine-histidine dendron modified chitosan for improving transfection efficiency in HEK293 cells.  |  Chang, KL., et al. 2011. J Control Release. 156: 195-202. PMID: 21802461
  4. Building parity between brand and generic peptide products: Regulatory and scientific considerations for quality of synthetic peptides.  |  Wu, LC., et al. 2017. Int J Pharm. 518: 320-334. PMID: 28027918
  5. Development of Conformationally Constrained α-RgIA Analogues as Stable Peptide Antagonists of Human α9α10 Nicotinic Acetylcholine Receptors.  |  Zheng, N., et al. 2020. J Med Chem. 63: 8380-8387. PMID: 32597184
  6. Combining high throughput array synthesis and growth algorithm to discover TNF-α binders with new structures and properties.  |  Lin, W., et al. 2023. Eur J Med Chem. 248: 115078. PMID: 36623330

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fmoc-beta-Ala-OH, 5 g

sc-294780
5 g
$31.00

Fmoc-beta-Ala-OH, 25 g

sc-294780A
25 g
$102.00