Fmoc-Ala-Ala-OH (CAS 87512-31-0)
QUICK LINKS
Fmoc-Ala-Ala-OH is a dipeptide derivative used as a building block in peptide synthesis. It functions as a protecting group for the amino group of the N-terminal amino acid, allowing for selective deprotection and subsequent coupling reactions. Fmoc-Ala-Ala-Oh plays a role in solid-phase peptide synthesis by facilitating the stepwise elongation of peptide chains. Its mechanism of action involves the temporary masking of the N-terminal amino group, preventing unwanted side reactions during the peptide assembly process. Fmoc-Ala-Ala-OH interacts at the molecular level by forming stable amide bonds with the carboxyl group of the C-terminal amino acid, enabling the controlled and sequential addition of amino acids to the growing peptide chain.
Fmoc-Ala-Ala-OH (CAS 87512-31-0) References
- Identification of Fmoc-beta-Ala-OH and Fmoc-beta-Ala-amino acid-OH as new impurities in Fmoc-protected amino acid derivatives. | Hlebowicz, E., et al. 2005. J Pept Res. 65: 90-7. PMID: 15686539
- Covalent Structure and Bioactivity of the Type AII Lantibiotic Salivaricin A2. | Geng, M., et al. 2018. Appl Environ Microbiol. 84: PMID: 29269497
- A General Method to Prepare Peptide-Based Supramolecular Hydrogels. | Yuan, D., et al. 2018. Methods Mol Biol. 1777: 175-180. PMID: 29744834
- Programmed assembly of synthetic protocells into thermoresponsive prototissues. | Gobbo, P., et al. 2018. Nat Mater. 17: 1145-1153. PMID: 30297813
- Oscillating the local milieu of polymersome interiors via single input-regulated bilayer crosslinking and permeability tuning. | Liu, G., et al. 2022. Nat Commun. 13: 585. PMID: 35102153
- Cyanoacetamide-based oxime carbonates: an efficient, simple alternative for the introduction of Fmoc with minimal dipeptide formation | Khattab, S. N., Subirós-Funosas, R., El-Faham, A., & Albericio, F. 2012. Tetrahedron. 68(14): 3056-3062.
- Extending the pool of compatible peptide hydrogels for protein crystallization | Escolano-Casado, G., Contreras-Montoya, R., Conejero-Muriel, M., Castellví, A., Juanhuix, J., Lopez-Lopez, M. T.,.. & Gavira, J. A. 2019. Crystals. 9(5): 244.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fmoc-Ala-Ala-OH, 1 g | sc-294775 | 1 g | $300.00 | |||
Fmoc-Ala-Ala-OH, 5 g | sc-294775A | 5 g | $1060.00 |