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Fmoc-6-Ahx-OH, short for Fmoc-6-aminohexanoic acid, is a compound utilized in the field of peptide synthesis. It is particularly valued in solid-phase peptide synthesis (SPPS) where it acts as a linker molecule, connecting the growing peptide chain to the resin support. The Fmoc group in Fmoc-6-Ahx-OH is a protective group that shields the amino functionality during the synthesis process, and it can be selectively removed under basic conditions when necessary for the coupling of additional amino acids. This compound allows for the introduction of a spacer arm between the peptide and the solid support, which can enhance the accessibility of enzymes and antibodies to the peptide, a feature that is beneficial in subsequent bioassays. Researchers also employ Fmoc-6-Ahx-OH to study the effects of incorporating spacer arms into peptides, which can influence their biological activity, solubility, and overall conformation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fmoc-6-Ahx-OH, 5 g | sc-294771 | 5 g | $97.00 | |||
Fmoc-6-Ahx-OH, 25 g | sc-294771A | 25 g | $291.00 |