Fmoc-4,5-dehydro-D-Leucine (CAS 917099-00-4)

Fmoc-4,5-dehydro-D-Leucine is an Fmoc protected leucine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Leucine is one of the more simple amino acids - an isobutyl group as the side chain. This smaller side chain confers a high degree of flexibility, and imparts a moderate hydrophobic effect when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.Fmoc-4,5-dehydro-D-Leucine, or Fmoc-DhLeu, is an artificial amino acid derived from leucine. It has gained significant prominence in the field of biochemistry and molecular biology research. his amino acid plays a vital role in investigating protein and other biological molecule structures and functions. Moreover, it finds widespread application in the development of peptide-based drugs and therapeutic agents due to its ability to form peptide bonds under mild conditions. Derived from leucine, a naturally occurring amino acid, Fmoc-4,5-dehydro-D-Leucine possesses a hydrophobic side chain that contributes to the stability of peptide bonds in the presence of water.